Neural substrates activated by viewing others expressing fatigue: A magnetoencephalography study
Neural substrates activated by viewing others expressing fatigue: A magnetoencephalography study
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DOI：
10.1016/j.brainres.2012.03.031
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发表时间：
2012-05-21
期刊：
影响因子：
2.9
通讯作者：
Watanabe, Yasuyoshi
中科院分区：
文献类型：
--
作者：
Ishii, Akira;Tanaka, Masaaki;Watanabe, Yasuyoshi
疲劳感的神经基础尚未完全确定。多项证据表明，看到他人的情绪变化会激活涉及经历类似情绪的大脑区域。我们假设存在一个关于疲劳感的镜像系统，并且与疲劳感相关的大脑区域可能会通过观看其他人表达疲劳而被激活。在这项研究中，我们试图通过使用脑磁图（MEG）观察其他疲劳的个体来识别激活的神经基质。十二名健康参与者在提供书面知情同意书后参加了我们的研究。在 MEG 记录期间，他们观看了投影在屏幕上的一组图片。这些照片以随机顺序呈现，照片中的人表情疲惫或中性。当参与者观看表情疲劳的人的照片时，我们能够在每张图片呈现开始后约 300 毫秒估计 12 名参与者中的 9 名后扣带皮层 (PCC) 中的等效电流偶极子 (ECD)。当他们观看表情中性的人的照片时，我们无法估计任何参与者相应的 ECD。 PCC 是通过观察他人表达疲劳而激活的大脑区域，这表明感觉到和观察到的疲劳存在共同的神经基质。 (C) 2012 Elsevier B.V. 保留所有权利。
The neural substrates of the fatigue sensation have not been totally identified. Several lines of evidence demonstrate that seeing emotional changes in others activates brain regions involved in experiencing similar emotions. We hypothesized that there exists a mirror system regarding the fatigue sensation and that brain regions associated with the fatigue sensation may be activated by viewing other individuals expressing fatigue. In this study, we attempted to identify the neural substrates activated by viewing other fatigued individuals using magnetoencephalography (MEG). Twelve healthy participants were enrolled in our study after providing written informed consent. During MEG recordings, they viewed a set of pictures projected on a screen. The pictures, which were presented in a randomized order, were of a person with a fatigued or neutral facial expression. When participants viewed pictures of people with fatigued expressions, we were able to estimate equivalent current dipoles (ECDs) in the posterior cingulate cortex (PCC) in 9 of 12 participants approximately 300 ms after the onset of each picture presentation. When they viewed pictures of people with neutral expressions, we were not able to estimate corresponding ECDs for any participant. The PCC is the brain region activated by viewing others expressing fatigue, suggesting existence of the shared neural substrates of felt and observed fatigue. (C) 2012 Elsevier B.V. All rights reserved.