Cryosurgical ablation of atrioventricular nodal reentry: histologic localization of the proximal common pathway.
Cryosurgical ablation of atrioventricular nodal reentry: histologic localization of the proximal common pathway.
复制标题
房室结折返的冷冻手术消融：近端共同通路的组织学定位。
DOI：
10.1161/01.cir.77.6.1356
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发表时间：
1988
期刊：
影响因子：
37.8
通讯作者：
Cox,JL
中科院分区：
文献类型：
--
作者：
Holman,WL;Hackel,DB;Lease,JG;Ikeshita,M;Cox,JL
先前已经描述了使用冷冻手术的方法来选择性地消融房室结折返性心动过速，同时保留完整的房室传导。本研究的目的是确定冷冻损伤的组织学特征与专门的传导系统的关系。在12只成年狗中，沿Koch三角的周边沿着放置一系列9个离散的冷冻损伤，同时连续监测希氏束电图。所有动物均在手术中存活，并保持完整的房室传导。在手术后14周，将心脏切片并检查。在所有12只动物中，下房间隔中存在致密纤维组织的汇合团，其紧邻但不涉及房室结-希氏束。证实了使用这种冷冻外科技术消融结周组织并保留专门的传导系统。冷冻消融的结周组织可能代表房室结折返性心动过速回路的近端共同通路。
A method using cryosurgery has been previously described to selectively ablate atrioventricular nodal reentry tachycardia while preserving intact atrioventricular conduction. The purpose of the present study was to define the histologic features of the cryolesions in relationship to the specialized conduction system. In 12 adult dogs a series of nine discrete cryolesions was placed along the perimeter of the triangle of Koch while continuously monitoring the His bundle electrogram. All animals survived the operation and maintained intact atrioventricular conduction. At 14 weeks after surgery the hearts were sectioned and examined. In all 12 animals there was a confluent mass of dense fibrous tissue present in the lower atrial septum that was in immediate proximity to but did not involve the atrioventricular node-His bundle. The ablation of perinodal tissue with preservation of the specialized conduction system with the use of this cryosurgical technique was confirmed. It is likely that the cryoablated perinodal tissue represents the proximal common pathway of the circuit for atrioventricular nodal reentry tachycardia.