A rare cause of dysphagia: malignant pleural mesothelioma in the posterior mediastinum.
A rare cause of dysphagia: malignant pleural mesothelioma in the posterior mediastinum.
复制标题
吞咽困难的罕见原因：后纵隔恶性胸膜间皮瘤。
DOI：
10.1016/j.athoracsur.2010.03.082
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Maeda,Hiroya
中科院分区：
文献类型：
--
作者：
Hayama,Makio;Maeda,Hiroya
一名69岁的男子因吞咽困难和呕吐到急诊室就诊。计算机断层扫描显示后纵隔肿块周围的食管下部。内视镜检查显示食道下段狭窄，并无恶性黏膜病变。胸腔镜下纵膈腔肿块活检未能得到病理诊断。左侧胸腔积液中的透明质酸浓度明显较高（755 mg/L），这是一个强烈提示恶性间皮瘤的发现。初次入院后四个月，在左胸壁发现一个皮下结节，并进行了活检。病理组织学及免疫组织化学检查结果均符合胸膜恶性间皮瘤的诊断。
A 69-year-old man presented to the emergency room with dysphagia and vomiting. A computed tomographic scan revealed a posterior mediastinal mass surrounding the lower portion of the esophagus. Endoscopic examination demonstrated narrowing of the lower esophagus without malignant mucosal lesions. Thoracoscopic biopsies of the mediastinal mass failed to yield a pathologic diagnosis. The hyaluronic acid concentration in the left pleural effusion was remarkably high (755 mg/L), which is a finding strongly suggestive of malignant mesothelioma. Four months after the initial admission, a subcutaneous nodule was found in the left chest wall and a biopsy was taken. The histopathologic and immunohistochemical findings of the biopsy were consistent with the diagnosis of pleural malignant mesothelioma.