Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted echo-planar MR with three values of gradient b-factor
Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted echo-planar MR with three values of gradient b-factor
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DOI：
10.1002/jmri.20682
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发表时间：
2006-09-01
影响因子：
4.4
通讯作者：
Horikoshi, Hiroyuki
中科院分区：
文献类型：
--
作者：
Moteki, Takao;Horikoshi, Hiroyuki
目的：为了确定是否扩散加权回波平面（EP）MR图像与非常小，小，大梯度b-因子是有用的评估肝脏病变和肝实质。材料和方法：96个肝脏病灶的弥散（D）和流动自旋（D*）表观弥散系数的近似值（26例肝细胞癌[HCC]，28例转移瘤，26例血管瘤和16例囊肿）和78例肝实质的非病变区域根据EP图像计算了50例非癫痫患者和28例癫痫患者（针对梯度b因子3、50和300秒/mm（2）进行了修改）。肝囊肿和非炎性肝脏的平均D* 值在统计学上高于肝细胞癌、血管瘤、转移瘤和炎性肝脏（P < 0.05，Scheff，事后分析）。肝囊肿的平均D值显著高于HCC、转移瘤、非炎性肝和炎性肝（P < 0.05）。肝血管瘤的平均D值明显高于HCC、非增生性肝和增生性肝（P < 0.05）。结论：D* 值与D值相结合，可用于评价肝脏病变和肝实质的弥散和流动自旋性质。
Purpose: To determine whether diffusion-weighted echoplanar (EP) MR images with very small, small, and large gradient b-factors are useful in evaluating hepatic lesions and hepatic parenchyma.Materials and Methods: Approximate values of the apparent diffusion coefficients for diffusion (D) and for flowing spins (D*) for 96 hepatic lesions (26 hepatocellular carcinomas [HCCs], 28 metastases, 26 hemangiomas, and 16 cysts) and the non-lesion-bearing regions of parenchyma in 78 livers (50 noncirrhotic and 28 cirrhotic) were calculated from EP images (modified for gradient b-factors of 3, 50, and 300 second/mm(2)).Results: Liver cysts and noncirrhotic livers showed statistically higher mean D* values than HCCs, hemangiomas, metastases, and cirrhotic livers (P < 0.05 on Scheff, post hoc analysis). Liver cysts showed statistically higher mean D values than HCCs, metastases, noncirrhotic livers, and 1 cirrhotic livers (P < 0.05). Liver hemangiomas showed statistically higher mean D values than HCCs, noncirrhotic livers, and cirrhotic livers (P < 0.05).Conclusion: The D* value in addition to the D value may be useful for evaluating the nature of diffusion and flowing spins in hepatic lesions and hepatic parenchyma.