Racial disparities in pregnancy outcomes among women with rheumatic diseases: A systematic literature review.
Racial disparities in pregnancy outcomes among women with rheumatic diseases: A systematic literature review.
复制标题
风湿病女性妊娠结局的种族差异：系统文献综述。
DOI：
10.1016/j.semarthrit.2023.152193
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发表时间：
2023
影响因子：
5
通讯作者：
Singh,Namrata
中科院分区：
文献类型：
--
作者：
Shen,Gloria;Swaminathan,Maya;Huang,Irvin;Louden,Diana;Feterman,Dominique;Tahir,MuhammadWaqas;Singh,Namrata
目的对患有风湿病的女性不良妊娠结局（APO）的种族差异了解有限。我们研究的目的是进行系统的文献综述，以评估种族对风湿病女性 APO 的影响。方法检索数据库以查找风湿病女性中按种族分层的 APO 报告。初步检索于 2020 年 7 月进行，更新于 2021 年 3 月。对最终纳入的文章进行了全文审查，并使用标准数据抽象形式从每项研究中提取数据。结果共有 39,720 名患者的 10 项研究符合我们的资格标准。与白人相比，患有风湿病的少数族裔更容易出现 APO。在患有系统性红斑狼疮 (SLE) 的女性中，黑人女性出现 APO 的几率最高，尤其是那些同时诊断出抗磷脂综合征的女性。由于多种因素，包括研究之间的异质性，无法进行汇总荟萃分析。结论：与白人相比，患有风湿病的少数族裔更容易患 APO。一个限制是 APO 缺乏标准化标准，这阻碍了研究之间的直接比较。除系统性红斑狼疮以外，患有风湿性疾病的女性中 APO 的数据也很少。需要进一步研究来探索这些种族差异的驱动因素，以便为最需要帮助的人提供有针对性的解决方案。
ObjectiveThere is a limited understanding of racial disparities in adverse pregnancy outcomes (APO) among women with rheumatic diseases. The aim of our study was to conduct a systematic literature review to evaluate the impact of race on APO in women with rheumatic diseases.MethodsDatabases were searched to find reports of APO stratified by race among women with rheumatic diseases. The initial searches were conducted in July 2020 and updated in March 2021. Of the final included articles, the full text was reviewed, and data was extracted from each study using a standard data abstraction form.ResultsTen studies with a total of 39,720 patients met our eligibility criteria. There was a greater propensity for APO in racial minorities with rheumatic diseases compared to their White counterparts. Among women with systemic lupus erythematosus (SLE), Black women had the highest odds of APOs, particularly those with a concomitant diagnosis of antiphospholipid syndrome. Pooled meta-analysis could not be done due to multiple factors, including heterogeneity between studies.ConclusionRacial minorities with rheumatic diseases are more prone to APO compared to their White counterparts. One limitation is the lack of standardized criteria for APO, which prohibited direct comparison between studies. There is also a paucity of data looking at APOs among women with rheumatic diseases other than SLE. Further research is needed to explore the drivers of these racial disparities to guide targeted solutions for those in the greatest need.