Pan-London Network for Psychosis-Prevention (PNP)
Pan-London Network for Psychosis-Prevention (PNP)
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DOI：
10.3389/fpsyt.2019.00707
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发表时间：
2019-10-11
影响因子：
4.7
通讯作者：
McGuire, Philip
中科院分区：
文献类型：
--
作者：
Fusar-Poli, Paolo;Estrade, Andres;McGuire, Philip
背景资料：精神病临床高危（CHR-P）范式的经验成功取决于在专业临床服务中同时整合风险病例的有效检测、准确的预后和有效的预防性治疗。CHR-P服务的特点是相对underinvestigated.Method：泛伦敦网络精神病预防（PNP）创建了城市CHR-P服务。对这些服务进行了调查，以收集以下信息：服务和服务范围的描述、外展、服务用户、干预措施和成果。结果进行了分析与描述性统计和Kaplan Meier failure function.Results：PNP包括五个CHR-P服务在两个NHS信托：外展和支持在伦敦南部（OASIS）在兰贝斯和南华克，OASIS在克罗伊登和刘易舍姆，塔哈姆雷特早期检测服务（THEDS），城市和哈克尼在风险精神状态服务（HEADS UP）和纽汉早期干预服务（NEIS）。国家警察为2，318，515名伦敦人（830，889人;年龄，16-35岁）提供服务，每年招募220名CHR-P个人（年龄，22.55岁）。独立团队（OASIS和THEDS）比与其他精神卫生服务机构（HEADS UP，NEIS）共享资源的团队更成熟和成功。各PNP服务机构的服务区、服务范围和服务用户的特点各不相同;所有这些机构都提供心理治疗，以预防精神病。PNP是支持几个CHR-P转化research projects.Conclusions：PNP是英国最大的CHR-P临床网络，它代表了一个参考基准，用于实施检测，预后和护理在现实世界的临床常规，以及将研究创新转化为实践。
Background: The empirical success of the Clinical High Risk for Psychosis (CHR-P) paradigm is determined by the concurrent integration of efficient detection of cases at-risk, accurate prognosis, and effective preventive treatment within specialized clinical services. The characteristics of the CHR-P services are relatively under-investigated.Method: A Pan-London Network for psychosis prevention (PNP) was created across urban CHR-P services. These services were surveyed to collect the following: description of the service and catchment area, outreach, service users, interventions, and outcomes. The results were analyzed with descriptive statistics and Kaplan Meier failure function.Results: The PNP included five CHR-P services across two NHS Trusts: Outreach and Support In South-London (OASIS) in Lambeth and Southwark, OASIS in Croydon and Lewisham, Tower Hamlets Early Detection Service (THEDS), City & Hackney At-Risk Mental State Service (HEADS UP) and Newham Early Intervention Service (NEIS). The PNP serves a total population of 2,318,515 Londoners (830,889; age, 16-35 years), with a yearly recruitment capacity of 220 CHR-P individuals (age, 22.55 years). Standalone teams (OASIS and THEDS) are more established and successful than teams that share their resources with other mental health services (HEADS UP, NEIS). Characteristics of the catchment areas, outreach and service users, differ across PNP services; all of them offer psychotherapy to prevent psychosis. The PNP is supporting several CHR-P translational research projects.Conclusions: The PNP is the largest CHR-P clinical network in the UK; it represents a reference benchmark for implementing detection, prognosis, and care in the real-world clinical routine, as well as for translating research innovations into practice.