Bioinformatics Applications Note Sequence Analysis Cd-hit Suite: a Web Server for Clustering and Comparing Biological Sequences

Bioinformatics Applications Note Sequence Analysis Cd-hit Suite: a Web Server for Clustering and Comparing Biological Sequences
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影响因子:
2.9
通讯作者:
Ying Huang;Beifang Niu;Ying Gao;L. Fu;Weizhong Li
Ying Huang;Beifang Niu;Ying Gao;L. Fu;Weizhong Li
中科院分区:
工程技术3区
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作者:
Ying Huang;Beifang Niu;Ying Gao;L. Fu;Weizhong Li

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CD-HIT是一个广泛使用的程序,用于聚类和比较大型生物序列数据集。为了进一步帮助CD-HIT用户,我们对该程序进行了重大改进,使其具有更多的功能和更好的准确性,可扩展性和灵活性。最重要的是,我们开发了一个新的Web服务器,CD-HIT套件,用于聚类用户上传的序列数据集或将其与不同身份级别的另一个数据集进行比较。用户现在可以在Web浏览器中交互式地探索集群。我们还为不同身份级别的几个公共数据库(NCBI NR,Swissprot和PDB)提供可下载的集群。
CD-HIT is a widely used program for clustering and comparing large biological sequence datasets. In order to further assist the CD-HIT users, we significantly improved this program with more functions and better accuracy, scalability and flexibility. Most importantly, we developed a new web server, CD-HIT Suite, for clustering a user-uploaded sequence dataset or comparing it to another dataset at different identity levels. Users can now interactively explore the clusters within web browsers. We also provide downloadable clusters for several public databases (NCBI NR, Swissprot and PDB) at different identity levels.