DETERMINANTS OF INTRABOLUS PRESSURE DURING ESOPHAGEAL PERISTALTIC BOLUS TRANSPORT
DETERMINANTS OF INTRABOLUS PRESSURE DURING ESOPHAGEAL PERISTALTIC BOLUS TRANSPORT
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DOI：
10.1152/ajpgi.1993.264.3.g407
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发表时间：
1993-03-01
影响因子：
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通讯作者：
ARNDORFER, RC
中科院分区：
文献类型：
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作者：
REN, JL;MASSEY, BT;ARNDORFER, RC
以前对人体食管液团转运的测压研究通常忽略了团内压力与管腔闭塞、收缩食管段内压力之间的流体动力学差异。在这项研究中，我们同时获得了仰卧位正常志愿者使用不同的推注体积和粘度和腹部压迫的食管视频荧光镜和腔内测压记录。团内压随团注体积、粘度和腹部压迫而增加。食管直径随团注体积的增大而增大，这种增大与团注内压力的增大相关。推注内压在推注尾部最高。峰值腔内压高于基础团内压>20 mmHg几乎总是与有效舒张相关，而该压差的值
Previous manometric studies of esophageal fluid bolus transport in humans have generally ignored the hydrodynamic distinction between intrabolus pressure and pressure within the lumen-occluded, contracting esophageal segment. In this study we obtained concurrent esophageal videofluoroscopic and intraluminal manometric recordings in supine normal volunteers using different bolus volumes and viscosities and abdominal compression. Intrabolus pressure increased with bolus volume, viscosity, and abdominal compression. Esophageal diameter increased with larger bolus volumes, and this increase was correlated with increases in intrabolus pressure. Intrabolus pressure was highest in the bolus tail. Peak intraluminal pressures >20 mmHg above basal intrabolus pressure almost invariably were associated with effective peristalsis, whereas values of this pressure differential