GABA AND GAD-LIKE IMMUNOREACTIVITY IN THE PRIMATE RETINA
GABA AND GAD-LIKE IMMUNOREACTIVITY IN THE PRIMATE RETINA
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DOI：
10.1007/bf00500621
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发表时间：
1987-01-01
期刊：
影响因子：
--
通讯作者：
WU, JY
中科院分区：
文献类型：
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作者：
AGARDH, E;EHINGER, B;WU, JY
本文研究了狒狒、食蟹猴和人视网膜的GABA免疫反应性，并与GD免疫反应性进行了比较。具有对应于无长突细胞的位置的细胞被染色，以及内丛状层中的突起和神经节细胞层中的一些细胞。外丛状层和一些具有水平细胞位置和形态的细胞也呈免疫反应阳性。在双极样细胞中也观察到染色，在人类中，当使用GABA抗血清时，在视网膜中央部分的切片中最清楚。水平细胞和双极样细胞可能在灵长类动物视网膜GABA能传递中起着以前未被怀疑的作用。
GABA immunoreactivity was studied and compared with GD immunoreactivity in the retinae of baboon, cynommolgus monkey and man. The central and peripheral parts of the retinae were investigated separately in cynomolgus monkey and in man. The same kinds of structure were stained with both antisera. Cells with a position corresponding to amacrine cells were stained, as well as processes in the inner plexiform layer and some cells in the ganglion cell layer. The outer plexiform layer and some cells with the position and configuration of horizontal cells also appeared immunoreactive. Staining was also observed in bipolar-like cells, in man most clearly when using the GABA antiserum in sections from the central parts of the retina. It is possible that horizontal cells, as well as bipolar-like cells, may play a previously unsuspected role in GABAergic transmission in the primate retina.