Printability of calcium phosphate powders for three-dimensional printing of tissue engineering scaffolds
Printability of calcium phosphate powders for three-dimensional printing of tissue engineering scaffolds
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DOI：
10.1016/j.actbio.2011.08.027
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发表时间：
2012-01-01
影响因子：
9.7
通讯作者：
Mueller, Ralph
中科院分区：
文献类型：
--
作者：
Butscher, Andre;Bohner, Marc;Mueller, Ralph
三维打印（3DP）是生产组织工程支架的通用方法。在3DP中，固体通过选择性地喷射到粉末床上的液体的反应产生。尽管粉末性质的重要性，但迄今为止，对粉末性质与印刷结果之间的关系的理解相对较差。本文旨在通过研究关键粉末参数（粒度、流动性、粗糙度、润湿性）与打印精度之间的联系来提高这种理解。这些粉末参数被确定为具有最终3DP结果的预测值的关键因素。对于20-35 μ m范围内的平均粒度、1.3-1.4范围内的压实率、5-7范围内的流动性和10-25 μ m的粉末床表面粗糙度，可以预期有希望的结果。最后，可能的步骤和策略，在推动有关提高质量的3DP的物理限制的地址和讨论。(C)2011 Acta Materialia Inc.由爱思唯尔有限公司出版。保留所有权利。
Three-dimensional printing (3DP) is a versatile method to produce scaffolds for tissue engineering. In 3DP the solid is created by the reaction of a liquid selectively sprayed onto a powder bed. Despite the importance of the powder properties, there has to date been a relatively poor understanding of the relation between the powder properties and the printing outcome. This article aims at improving this understanding by looking at the link between key powder parameters (particle size, flowability, roughness, wettability) and printing accuracy. These powder parameters are determined as key factors with a predictive value for the final 3DP outcome. Promising results can be expected for mean particle size in the range of 20-35 mu m, compaction rate in the range of 1.3-1.4, flowability in the range of 5-7 and powder bed surface roughness of 10-25 mu m. Finally, possible steps and strategies in pushing the physical limits concerning improved quality in 3DP are addressed and discussed. (C) 2011 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.