Metal oxide nanomaterials in seawater: Linking physicochemical characteristics with biological response in sea urchin development
Metal oxide nanomaterials in seawater: Linking physicochemical characteristics with biological response in sea urchin development
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DOI：
10.1016/j.jhazmat.2011.06.080
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发表时间：
2011-09-15
影响因子：
13.6
通讯作者：
Cherr, Gary N.
中科院分区：
文献类型：
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作者：
Fairbairn, Elise A.;Keller, Arturo A.;Cherr, Gary N.
纳米材料(NMS)在环境介质中的命运和行为对毒性有重要影响。到目前为止，大多数水生研究都集中在淡水系统中的NM行为。然而，海水的pH和盐度差异会影响NMS的溶解和聚集。在这项研究中，海水中金属氧化物NMS的物理特性与其对发育中的海胆的毒性有关。高达10 mg/L的金属氧化物纳米二氧化钛和氧化铈对白海胆的胚胎没有毒性。而纳米氧化锌对这些胚胎的毒性较强(EC(50)=99.5mUg/L)。纳米氧化锌的毒性与体相和可溶性锌(2+)的毒性无显著差异，表明纳米氧化锌的毒性可归因于可溶锌。此外，溶解度数据表明，在我们的海胆胚胎实验中使用的浓度下，氧化锌纳米颗粒在海水中迅速且完全溶解。本研究还表明，与纯的氧化锌纳米管相比，铁掺杂的纳米管在海水中的溶解度较低，但没有相应的毒性降低。(C)2011爱思唯尔B.V.保留所有权利。
The fate and behavior of nanomaterials (NMs) in environmental media has important consequences for toxicity. The majority of aquatic research to date has focused on NM behavior in freshwater systems. However, pH and salinity differences of seawater affect dissolution and aggregation of NMs. In this study, physical characteristics of metal oxide NMs in seawater were linked with their toxicity to developing sea urchins. The metal oxide NMs TiO(2) and CeO(2) up to 10 mg/L were not toxic to the embryos of the white sea urchin (Lytechinus pictus). In contrast, ZnO NM was highly toxic to these embryos (EC(50) = 99.5 mu g/L). The toxicity of ZnO NM was not significantly different from bulk ZnO or soluble Zn(2+) (from ZnSO(4)center dot 7H(2)O), suggesting that the toxicity of ZnO NM can be attributed to soluble Zn(2+). Furthermore, solubility data indicate that at the concentrations used in our sea urchin embryo experiments, ZnO NM was rapidly and completely solubilized in seawater. The present study also demonstrated that Fe-doped NMs were less soluble in seawater compared to pure ZnO NMs, but there was no concomitant reduction in toxicity. (C) 2011 Elsevier B.V. All rights reserved.