Contactless, programmable acoustofluidic manipulation of objects on water.
Contactless, programmable acoustofluidic manipulation of objects on water.
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DOI：
10.1039/c9lc00465c
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发表时间：
2019-10
期刊：
影响因子：
6.1
通讯作者：
Peiran Zhang;Chuyi Chen;Feng Guo;Julien Philippe;Yuyang Gu;Zhenhua Tian;Hunter Bachman;Liqiang Ren;Shujie Yang;Zhanwei Zhong;Po-Hsun Huang;N. Katsanis;K. Chakrabarty;T. Huang
中科院分区：
文献类型：
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作者：
Peiran Zhang;Chuyi Chen;Feng Guo;Julien Philippe;Yuyang Gu;Zhenhua Tian;Hunter Bachman;Liqiang Ren;Shujie Yang;Zhanwei Zhong;Po-Hsun Huang;N. Katsanis;K. Chakrabarty;T. Huang
小物体的无接触操作（例如，细胞、组织和液滴）消除了与结构的物理接触和不希望的表面吸附。开创性的基于声学的无接触操作技术（例如，声悬浮）使得能够进行可编程的操作，但是受到蒸发、庞大的换能器和空气中低效的声耦合的限制。在这里，我们报告了一个声流体机制的非接触式操纵小物体的水。在铌酸锂（LiNbO3）基片上制作了一个空心方形叉指换能器（IDT），将其浸入水中，用作声源产生声波，并用作微泵在±x和±y正交方向上泵送流体。因此，在定向声波传播之后，可以在±x和±y方向上单向（水平地）推动邻近激发的IDT浮动的物体。通过将IDT单元图案化成6 × 6阵列来开发流体处理器。我们展示了对油滴和斑马鱼幼虫的非接触式、可编程操作。这种基于声流体的操作为材料和小生物样品的非接触式可编程处理开辟了道路。
Contact-free manipulation of small objects (e.g., cells, tissues, and droplets) using acoustic waves eliminates physical contact with structures and undesired surface adsorption. Pioneering acoustic-based, contact-free manipulation techniques (e.g., acoustic levitation) enable programmable manipulation but are limited by evaporation, bulky transducers, and inefficient acoustic coupling in air. Herein, we report an acoustofluidic mechanism for the contactless manipulation of small objects on water. A hollow-square-shaped interdigital transducer (IDT) is fabricated on lithium niobate (LiNbO3), immersed in water and used as a sound source to generate acoustic waves and as a micropump to pump fluid in the ±x and ±y orthogonal directions. As a result, objects which float adjacent to the excited IDT can be pushed unidirectionally (horizontally) in ±x and ±y following the directed acoustic wave propagation. A fluidic processor was developed by patterning IDT units in a 6-by-6 array. We demonstrate contactless, programmable manipulation on water of oil droplets and zebrafish larvae. This acoustofluidic-based manipulation opens avenues for the contactless, programmable processing of materials and small biosamples.