Lipoproteins and lipoprotein metabolism in periodontal disease.
Lipoproteins and lipoprotein metabolism in periodontal disease.
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DOI：
10.2217/clp.10.27
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发表时间：
2010-06
影响因子：
--
通讯作者：
Barbour S
中科院分区：
文献类型：
--
作者：
Griffiths R;Barbour S
A growing body of evidence indicates that the incidence of atherosclerosis is increased in subjects with periodontitis – a chronic infection of the oral cavity. This article summarizes the evidence that suggests periodontitis shifts the lipoprotein profile to be more proatherogenic. LDL-C is elevated in periodontitis and most studies indicate that triglyceride levels are also increased. By contrast, antiatherogenic HDL tends to be low in periodontitis. Periodontal therapy tends to shift lipoprotein levels to a healthier profile and also reduces subclinical indices of atherosclerosis. In summary, periodontal disease alters lipoprotein metabolism in ways that could promote atherosclerosis and cardiovascular disease.
