Nanoscale biomolecular structures on self-assembled monolayers generated from modular pegylated disulfides.
Nanoscale biomolecular structures on self-assembled monolayers generated from modular pegylated disulfides.
复制标题
由模块化聚乙二醇化二硫化物生成的自组装单分子层上的纳米级生物分子结构。
DOI：
10.1002/chem.200902439
复制
发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Wong LS
中科院分区：
文献类型：
--
作者：
Wong LS
A solid‐phase synthetic strategy was developed that uses modular building blocks to prepare symmetric oligo(ethylene glycol)‐terminated disulfides with a variety of lengths and terminal functionalities. The modular disulfides, composed of alkyl amino groups linked by an amide group to oligoethylene chains were used to generate self‐assembled monolayers (SAMs), which were characterised to determine their applicability for biomolecular applications. X‐ray photoelectron spectroscopy (XPS) of the SAMs obtained from these molecules demonstrated improved stability towards displacement by 16‐hexadecanethiol, while surface plasmon resonance (SPR) analyses of SAMs prepared with the hydroxy‐terminated oligoethylene disulfide showed equal resistance to non‐specific protein adsorption in comparison to 11‐mercaptoundecyl tri(ethylene glycol). SAMs made from these adsorbates were amenable to nanoscale patterning by scanning near‐field photolithography (SNP), facilitating the fabrication of nanopatterned, protein‐functionalised surfaces. Such SAMs may be further developed for bionanotechnology applications such as the fabrication of nanoscale biological arrays and sensor devices.
登录
查看更多内容
DOI：
10.1073/pnas.072695699
发表时间：
2002-04-16
影响因子：
11.1
作者：
Liu, GY;Amro, NA
通讯作者：
Amro, NA
影响因子：
--
作者：
Li, YY;Llewellyn, NM;Spencer, JB
通讯作者：
Spencer, JB
特定分子间相互作用对寡聚乙二醇封端的烷硫醇在金上的自组装和相行为的影响
影响因子：
3.3
作者：
R. Valiokas;S. Svedhem;M. Östblom;A. Svensson;B. Liedberg
通讯作者：
B. Liedberg
HYCRON，一种用于高效固相合成受保护肽和糖肽的烯丙基锚
影响因子：
3.6
作者：
O. Seitz;H. Kunz
通讯作者：
H. Kunz
影响因子：
9.9
作者：
Hoffmann, C;Tovar, GEM
通讯作者：
Tovar, GEM