Detection of Neisseria gonorrhoeae in the pharynx and saliva: implications for gonorrhoea transmission

Detection of Neisseria gonorrhoeae in the pharynx and saliva: implications for gonorrhoea transmission
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DOI:
10.1136/sextrans-2015-052399
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发表时间:
2016-08-01
影响因子:
3.6
通讯作者:
Fairley, Christopher K.
Fairley, Christopher K.
中科院分区:
医学2区
文献类型:
--
作者:
Chow, Eric P. F.;Lee, David;Fairley, Christopher K.

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目的本研究的目的是确定未经处理的咽拭子或唾液样本的比例阳性培养或核酸扩增试验(NAAT)淋病奈瑟氏菌后14天内首次培养阳性咽拭子。方法男性谁与男性谁测试阳性咽淋病在墨尔本性健康中心(MSHC)并在2014年10月13日至2015年3月25日之间的14天内返回MSHC接受治疗的患者纳入本研究。结果33份初筛阳性咽拭子标本中,32份唾液标本和31份咽拭子标本在14 d内经NAAT检测为阳性,14份咽拭子标本和6份唾液标本经培养检测为阳性。随着时间的推移,重复咽部培养样本中培养阳性的比例显著下降(p
Objectives This study aimed to determine the proportion of untreated pharyngeal swabs or saliva samples positive by culture or nucleic acid amplification tests ( NAATs) for Neisseria gonorrhoeae up to 14 days after an initial culture-positive pharyngeal swab.Methods Men who have sex with men who tested positive for pharyngeal gonorrhoea at Melbourne Sexual Health Centre ( MSHC) and returned to MSHC for treatment within 14 days between 13 October 2014 and 25 March 2015 were included in this study. Pharyngeal swabs and saliva samples were collected for culture and NAAT.Results Of 33 initially culture-positive pharyngeal swabs, 32 saliva samples and 31 pharyngeal swabs were positive by NAAT and 14 pharyngeal and 6 saliva samples were positive by culture within 14 days. There was a significant decline in the proportion of repeated pharyngeal culture samples positive by culture over time ( p