FACTORS IN CHILDHOOD AS PREDICTORS OF ASTHMA IN ADULT LIFE
FACTORS IN CHILDHOOD AS PREDICTORS OF ASTHMA IN ADULT LIFE
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DOI：
10.1136/bmj.309.6947.90
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发表时间：
1994-07-09
影响因子：
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通讯作者：
GILES, GG
中科院分区：
文献类型：
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作者：
JENKINS, MA;HOPPER, JL;GILES, GG
目的-确定在儿童时期测量的哪些因素可以预测成人生活中的哮喘。设计-一项超过25年的前瞻性研究，研究对象是在澳大利亚塔斯马尼亚7岁时首次研究的出生队列。受试者-1991-3岁29至32岁的1494名男性和女性(来自1968年塔斯马尼亚1961年出生和在塔斯马尼亚上学的儿童的随机分层样本的75%)。主要观察指标-自我报告哮喘或在过去12个月内喘息(当前哮喘)。结果-7岁之前患有哮喘或喘息的受试者，根据父母的报告，25.6%(190/741)的受试者报告成年后现在患有哮喘，而没有父母的受试者中10.8%(81/753)的人报告儿童时期患有哮喘(P
Objective-To determine which factors measured in childhood predict asthma in adult life.Design-Prospective study over 25 years of a birth cohort initially studied at the age of 7.Setting-Tasmania, Australia.Subjects-1494 men and women surveyed in 1991-3 when aged 29 to 32 (75% of a random stratified sample from the 1968 Tasmanian asthma survey of children born in 1961 and at school in Tasmania).Main outcome measures-Self reported asthma or wheezy breathing in the previous 12 months (current asthma).Result-Of the subjects with asthma or wheezy breathing by the age of 7, as reported by their parents 25.6% (190/741) reported current asthma as an adult compared with 10.8% (81/753) of subjects without parent reported childhood asthma (P