Adherence to Eye Drops Usage in Dry Eye Patients and Reasons for Non-Compliance: A Web-Based Survey.
Adherence to Eye Drops Usage in Dry Eye Patients and Reasons for Non-Compliance: A Web-Based Survey.
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DOI：
10.3390/jcm11020367
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发表时间：
2022-01-12
影响因子：
3.9
通讯作者：
On Behalf Of The Japan Dry Eye Society
中科院分区：
文献类型：
--
作者：
Uchino M;Yokoi N;Shimazaki J;Hori Y;Tsubota K;On Behalf Of The Japan Dry Eye Society
本研究旨在探讨干眼症（DED）眼药水的实际使用情况、滴眼行为的原因以及滴眼行为与主观症状之间的关系。这项基于网络的横断面研究收集了有关滴注行为、用药说明、滴注行为原因和主观症状的数据。总共有 2645 名参与者参加。按照药品说明书中规定的频率（指定频率）滴注的参与者比例为10.2%。不按规定频率滴注的最常见原因是为了缓解主观症状而按需滴注，61.3%的参与者是在感觉症状时滴注。定期以指定频率滴注的组的主观症状评分改善明显大于另一组（p = 0.0027），且另一组患者更年轻，隐形眼镜使用率和非处方眼药水使用率更高。总之，大多数参与者并没有按照指定的频率滴注 DED 滴眼液来缓解症状。为了获得适当的滴眼剂效果，眼科医生需要向患者灌输按照说明书上指定的频率定期滴注的重要性，同时考虑到患者的特征。
This study aimed to investigate the actual use of eye drops for dry eye disease (DED), the reasons for instillation behavior, and the relationship between instillation behavior and subjective symptoms. This web-based cross-sectional study collected data on instillation behavior, medication instruction, reasons for instillation behavior, and subjective symptoms. In total, 2645 participants were enrolled. The proportion of participants who instilled at the frequency specified in the package insert (the specified frequency) was 10.2%. The most common reason for not instilling at the prescribed frequency was as-needed instillation to alleviate subjective symptoms, and 61.3% of participants instilled when feeling symptoms. The improvement in the subjective symptoms score was significantly greater in the group that regularly instilled at the specified frequency than the other group (p = 0.0027), and patients in the other group were younger and had a higher rate of contact lens use and over-the-counter eye drops use. In conclusion, most participants did not instill the DED eye drops at the specified frequency to alleviate symptoms. In order to obtain the appropriate effect of eye drops, ophthalmologists need to impress upon patients the importance of regular instillation at the frequency specified in the package insert, while taking into account patient characteristics.
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影响因子：
5.6
作者：
NAKAMURA, M;MISHIMA, H;OTORI, T
通讯作者：
OTORI, T
DOI：
10.1089/108076803322279390
发表时间：
2003-08-01
影响因子：
2.3
作者：
Murakami, T;Fujihara, T;Nakata, K
通讯作者：
Nakata, K
影响因子：
6.4
作者：
Tsubota, Kazuo;Yokoi, Norihiko;Liu, Zuguo
通讯作者：
Liu, Zuguo
影响因子：
2.1
作者：
Murakami, T;Fujihara, T;Nakamura, M
通讯作者：
Nakamura, M
影响因子：
3.8
作者：
Kawashima, Motoko;Yamada, Masakazu;Tsubota, Kazuo
通讯作者：
Tsubota, Kazuo