Cellulose copper as bio-supported recyclable catalyst for the clickable azide-alkyne [3+2] cycloaddition reaction in water
Cellulose copper as bio-supported recyclable catalyst for the clickable azide-alkyne [3+2] cycloaddition reaction in water
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DOI：
10.1016/j.ijbiomac.2018.07.200
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发表时间：
2018-11-01
影响因子：
8.2
通讯作者：
Stiriba, Salah-Eddine
中科院分区：
文献类型：
--
作者：
Bahsis, Lahoucine;Ben El Ayouchia, Hicham;Stiriba, Salah-Eddine
天然存在的纤维素已被用作生物载体大分子，用于固定铜（I）或铜（II）离子，以在水中点击叠氮化物和炔衍生物。在这种点击机制下，1，4-二取代-1，2，3-三唑在室温下以优异的产率区域选择性地得到。反应后处理简单，生物非均相催化剂，已充分表征AAS，SEM，EDX和FT-IR可以很容易地分离和重复使用至少5次，而没有任何显着降低其活性和选择性，特别是在非常稳定的铜纤维素的情况下。(C)2018爱思唯尔B. V.保留所有权利。
Naturally-occurring cellulose has been employed as a bio-support macromolecule for the immobilization of either copper(I) or copper(II) ions in order to click azide and alkyne derivatives in water. Under such a click regime, 1,4-disubstitued-1,2,3-triazoles were obtained regioselectively in excellent yields at room temperature. The reaction work-up is simple and the bio-heterogeneous catalyst that has been fully characterized by AAS, SEM, EDX and FT-IR can be easily separated and reused at least five times without any significant decrease in its activity and selectivity, particularly in the case of the very stable CuI-Cellulose. (C) 2018 Elsevier B.V. All rights reserved.