Morphological and hemodynamic analysis of posterior communicating artery aneurysms prone to rupture: a matched case-control study
Morphological and hemodynamic analysis of posterior communicating artery aneurysms prone to rupture: a matched case-control study
复制标题
DOI：
10.1136/neurintsurg-2014-011450
复制
发表时间：
2016-01-01
影响因子：
4.8
通讯作者：
Huang, Qinghai
中科院分区：
文献类型：
--
作者：
Duan, Guoli;Lv, Nan;Huang, Qinghai
目的我们评估后交通动脉（PcomA）动脉瘤破裂和形态学和血流动力学参数之间的相关性，以评估相关的破裂风险indexs.Methods 6例PcomA动脉瘤，最终破裂（例）进行了研究后，最初被列入一个前瞻性的数据库，包括其三维（3D）成像破裂前。对于每例病例，随机选择4个偶然的稳定未破裂动脉瘤（对照），并根据临床因素进行匹配。对所有患者的三维图像进行重建，建立患者特异性模型。测量并计算6项形态学参数和3项血流动力学参数。结果动脉瘤直径越大（p=0.001），动脉瘤的长宽比越大（p= 0.018），椭圆度指数越大（p = 0.001），动脉瘤的破裂危险性越大（p= 0.001）。
Objectives We evaluated the correlation between posterior communicating artery (PcomA) aneurysm rupture and morphological and hemodynamic parameters to assess related rupture risk indices.Methods Six patients with PcomA aneurysms that ultimately ruptured (cases) were studied after initially being included in a prospective database including their three-dimensional (3D) imaging before rupture. For each case, four incidental stable unruptured aneurysms (controls) were randomly selected and matched based on clinical factors. The 3D images from all patients were reconstructed to establish the patient-specific model. Six morphologic parameters and three hemodynamic parameters were measured and calculated. A conditional logistic regression analysis was used to assess the individual risk of rupture.Results The analysis demonstrated a larger aneurysm size (p=0.001), higher aspect ratio (p=0.018), ellipticity index (p