Geriatric urolithiasis
Geriatric urolithiasis
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DOI：
10.1016/s0022-5347(01)68203-x
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发表时间：
1997-12-01
影响因子：
6.6
通讯作者：
Leslie, SW
中科院分区：
文献类型：
--
作者：
Gentle, DL;Stoller, ML;Leslie, SW
目的：我们定义了老年患者与泌尿系结石病之间的差异相比，一个年轻的coherent.Materials和方法：一个数据库，包括血清生化资料，24小时尿液分析和标准化的问卷调查，回顾性评价了超过6,000例连续的泌尿系结石病。这些老年患者中有三分之二有异常尿值，29%有孤立性低柠檬酸尿，而年轻组为17%。在老年结石形成患者中，76%有复发性尿路结石（平均3.5次结石发作），这与年轻可比组（77%，平均3.3次结石发作）相似。根据泌尿外科干预的需要，两组之间泌尿系结石疾病的严重程度相似。一般而言，与年轻患者相比，老年结石患者的首次结石发作时间较晚（50岁后）。老年患者尿酸结石的发病率增加，但鸟粪石结石的发病率相似。老年结石患者接受甲状旁腺手术的频率更高（2.7%对0.7%）。结论：老年和年轻结石患者复发性泌尿系结石的发生率、复发率和严重程度相似。老年结石患者孤立性低柠檬酸尿、尿酸结石和既往甲状旁腺切除术的发生率增加。老年结石人群不仅仅是年龄较大的年轻结石形成患者的延伸。相反，老年患者通常在生命后期经历第一次症状性结石发作。
Purpose: We define the differences between geriatric patients with urinary stone disease compared to a younger cohort.Materials and Methods: A data base, including serum biochemical profiles, 24-hour urinalyses and standardized questionnaires, was retrospectively evaluated from more than 6,000 consecutive patients with urinary stone disease.Results: Geriatric stone formers comprised 12% (721) of all stone patients. Two-thirds of these elderly patients had aberrant urinary values and 29% had isolated hypocitraturia compared to 17% in the younger group. Of geriatric stone forming patients 76% had recurrent urinary stones (mean 3.5 stone episodes), which was similar to the younger comparable group (77%, mean 3.3 stone episodes). The severity of urinary stone disease was similar between the 2 groups based on the need for urological intervention. Geriatric stone patients, in general, experienced the first stone episode later in life (after age 50 years) compared with younger patients. Elderly patients had an increased incidence of uric acid stones, but had a similar incidence of struvite calculi. Geriatric stone patients underwent parathyroid surgery more frequently (2.7 versus 0.7%). Geriatric stone forming patients rarely had renal failure.Conclusions: The incidence, recurrence and severity of recurrent urinary stone disease were similar between geriatric and younger stone forming patients. Geriatric stone patients had an increased incidence of isolated hypocitraturia, uric acid calculi and previous parathyroidectomy. The geriatric stone population is not merely an extension of younger stone forming patients presenting at an older age. Rather, geriatric patients commonly experience the first symptomatic stone episode later in life.