VALIDATING SCREENING INSTRUMENTS FOR NEUROEPIDEMIOLOGIC SURVEYS - EXPERIENCE IN SICILY

VALIDATING SCREENING INSTRUMENTS FOR NEUROEPIDEMIOLOGIC SURVEYS - EXPERIENCE IN SICILY
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DOI:
10.1016/0895-4356(92)90033-j
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发表时间:
1992-04-01
影响因子:
7.2
通讯作者:
DIPERRI, R
DIPERRI, R
中科院分区:
医学2区
文献类型:
--
作者:
MENEGHINI, F;ROCCA, WA;DIPERRI, R

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在西西里岛的一家医院,我们评估了一种用于帕金森病、周围神经病变、中风和癫痫患病率调查的筛查工具。研究对象为:(1)上述任一疾病的住院患者,调查其敏感性;(2)医院访客均无上述疾病,以调查特异性。比较的标准是根据规定的标准进行临床评价。训练有素的采访者管理筛选工具,要求受试者回答症状问题并执行简单的体力任务。对于问题和任务,帕金森病(n = 21)的敏感性估计为100%,周围神经病变(n = 22)的敏感性估计为96%,中风(n = 22)的敏感性估计为96%,癫痫(n = 22)的敏感性估计为86% (n = 21)。对问题集、任务集以及每个问题和任务分别计算类似的估计。尽管我们的方法有局限性,但我们得出的结论是,筛查仪器将足以满足其预期用途。
In a hospital setting in Sicily, we assessed a screening instrument developed for a prevalence survey of parkinsonism, peripheral neuropathies, stroke, and epilepsy. The subjects consisted of (1) hospital patients with any of the above-mentioned diseases, to investigate sensitivity; and (2) hospital visitors free of all these diseases, to investigate specificity. The standard for comparison was a clinical evaluation based on specified criteria. Trained interviewers administered the screening instrument, asking subjects to answer symptom questions and to perform simple physical tasks. For the questions and tasks together, the sensitivity estimates were 100% for parkinsonism (n = 21), 96% for peripheral neuropathies (n = 22), 96% for stroke (n = 22), and 96% for epilepsy (n = 22), while the specificity estimate was 86% (n = 21). Analogous estimates were computed for the set of questions, for the set of tasks, and for each question and task individually. Despite limitations in our approach, we concluded that the screening instrument would be adequate for its intended use.