HLA markers associated with progression to AIDS are also associated with susceptibility to cytomegalovirus retinitis
HLA markers associated with progression to AIDS are also associated with susceptibility to cytomegalovirus retinitis
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DOI：
10.1097/00002030-200309260-00020
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发表时间：
2003-09-26
期刊：
影响因子：
3.8
通讯作者：
Rodrigues, MLV
中科院分区：
文献类型：
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作者：
Fernandes, APM;Gonçalves, MAG;Rodrigues, MLV
ak5在患有或未表现出巨细胞病毒视网膜炎 (CMV-R) 的巴西艾滋病患者中评估了与从 HIV 感染快速进展为 AIDS 相关的 HLA 标记频率。总共有 124 名 AIDS 患者（44 名患有 CMV-R，80 名没有 CMV-R）接受了研究。与没有视网膜炎的患者相比，CMV-R 组中与艾滋病快速进展相关的 HLA 标记物显着增加。这些 HLA 标记物的存在可能会同时诱发 AIDS 和 CMV-R。
ak5The frequency of HLA markers associated with rapid progression from HIV infection to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not exhibiting cytomegalovirus retinitis (CMV-R). A total of 124 AIDS patients (44 with and 80 without CMV-R) were studied. HLA markers associated with rapid progression to AIDS were significantly increased in the CMV-R group compared with those without retinitis. The presence of these HLA markers may simultaneously predispose to AIDS and CMV-R.