Serum IgA and IgG antibodies to Treponema vincentii and Treponema denticola in adult periodontitis, juvenile periodontitis and periodontally healthy subjects.
Serum IgA and IgG antibodies to Treponema vincentii and Treponema denticola in adult periodontitis, juvenile periodontitis and periodontally healthy subjects.
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成人牙周炎、青少年牙周炎和牙周健康受试者血清中针对文森特螺旋体和齿状螺旋体的 IgA 和 IgG 抗体。
DOI：
10.1111/j.1600-051x.1986.tb00878.x
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发表时间：
1986
影响因子：
6.7
通讯作者：
Dougherty,P
中科院分区：
文献类型：
--
作者：
Lai,CH;Listgarten,MA;Evian,CI;Dougherty,P
对13例未经治疗的成人牙周炎(AP)患者和8例非牙周病(H)患者的菌斑指数(P1I)、牙龈指数(GI)、探诊深度(PD)和牙周探诊深度最大的6个表面的菌斑指数(P1I)、菌斑指数(GI)、牙周细菌形态分类计数(PD)进行了比较。血清抗体水平。激励和T。同时测定了这些受试者以及5例局限性青少年牙周炎(UP)患者血清中的牙周膜促乳素水平。AP患者的螺旋体和运动杆比例明显高于H患者，而球状细胞比例低于H患者。他们还表现出显著更高的P1I和GI得分以及更大的探测深度。抗体水平以标准血清归一化，并以酶联免疫吸附试验单位(EU)表示。与H组或LJP患者相比，AP患者对所有被测螺旋体菌株的IgA和Ig G抗体水平显著升高。H组和LJP组之间的抗体滴度对于任何测试菌株都没有显著差异。在接受测试的任何一种口腔螺旋体菌株的血清抗体效价与镜检确定的口腔螺旋体比例之间没有明显的相关性。
13 patients with untreated adult periodontitis (AP) were compared to 8 subjects free of periodontal disease (H) with respect to plaque index (P1I), gingival index (GI), probing depth (PD) and differential counts of subgingival bacterial morphotypes from a pooled sample of 6 surfaces with the greatest probing depth. Serum antibody levels toT. vincentiiandT. denticolastrains were also determined in these subjects as well as in the sera from 5 subjects with localized juvenile periodontitis (UP). Subjects with AP had significantly elevated proportions of spirochetes and motile rods and lower proportions of coccoid cells than H subjects. They also exhibited significantly higher P1I and GI scores and greater probing depths. Antibody levels were normalized against a standard serum and expressed as ELISA units (EU). IgA and IgG antibody levels to all tested spirochete strains were significantly elevated in AP subjects as compared to subjects in group H or subjects with LJP. No significant differences in antibody liters were detectable between the H and LJP groups with respect to any of the tested strains. No significant correlation could be demonstrated between serum antibody titers to any of the oral spirochete strains tested and the proportions of oral spirochetes determined microscopically.