Blood Pressure in Relation to Environmental Lead Exposure in the National Health and Nutrition Examination Survey 2003 to 2010
Blood Pressure in Relation to Environmental Lead Exposure in the National Health and Nutrition Examination Survey 2003 to 2010
复制标题
DOI：
10.1161/hypertensionaha.114.04023
复制
发表时间：
2015-01-01
期刊：
影响因子：
8.3
通讯作者：
Staessen, Jan A.
中科院分区：
文献类型：
--
作者：
Hara, Azusa;Thijs, Lutgarde;Staessen, Jan A.
鉴于美国环境铅暴露的下降，我们分析了国家健康和营养调查（2003-2010）的血压和高血压与血铅的关系。12725名参与者包括21.1%的黑人，20.5%的西班牙裔，58.4%的白人和48.7%的女性。与非黑人相比，黑人的收缩压和舒张压较高（126.5对123.9和71.9对69.6毫米汞柱），高血压患病率较高（44.7对36.8%）。白人的血铅低于非白人（1.46对1.57 μ g/dL），女性低于男性（1.25对1.80 μ g/dL）。在对所有参与者的多变量分析中，血铅加倍与女性收缩压和非白人舒张压升高（P = 0.09）相关。男性收缩压随血铅升高而升高（P
In view of the declining environmental lead exposure in the United States, we analyzed the National Health and Nutrition Examination Survey (2003-2010) for association of blood pressure and hypertension with blood lead. The 12 725 participants included 21.1% blacks, 20.5% Hispanics, 58.4% whites, and 48.7% women. Blacks compared with non-Blacks had higher systolic and diastolic pressures (126.5 versus 123.9 and 71.9 versus 69.6 mm Hg) and higher hypertension prevalence (44.7 versus 36.8%). Blood lead was lower in whites than in non-whites (1.46 versus 1.57 mu g/dL) and in women than in men (1.25 versus 1.80 mu g/dL). In multivariable analyses of all participants, blood lead doubling was associated with higher (P = 0.09) for systolic pressure in women and for diastolic pressure in non-whites. Among men, systolic pressure increased with blood lead (P