Enzyme classification using complex dynamic hemithioacetal systems.
Enzyme classification using complex dynamic hemithioacetal systems.
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使用复杂的动态半硫缩醛系统进行酶分类。
DOI：
10.1039/c6cc01823h
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Ramström,Olof
中科院分区：
文献类型：
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作者：
Zhang,Yan;Jayawardena,HSurangiN;Yan,Mingdi;Ramström,Olof
建立了一个复杂的动态半硫缩醛体系，用于评价脂肪酶在有机介质中的反应活性。结合模式识别方法，根据反应选择性和反应活性，将12种脂肪酶成功地分为4类。使用具有预测反应性的训练矩阵对探针脂肪酶进行进一步分类。
A complex dynamic hemithioacetal system was generated for the evaluation of lipase reactivities in organic media. In combination with pattern recognition methodology, twelve different lipases were successfully classified into four distinct groups following their reaction selectivities and reactivities. A probe lipase was further categorized using the training matrix with predicted reactivity.