Reduced ventral anterior cingulate and amygdala volumes in medication-naive females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study
Reduced ventral anterior cingulate and amygdala volumes in medication-naive females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study
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DOI：
10.1016/j.pscychresns.2007.03.005
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发表时间：
2007-10-15
影响因子：
2.3
通讯作者：
Blumberg, Hilary P.
中科院分区：
文献类型：
--
作者：
Tang, Yanqing;Wang, Fei;Blumberg, Hilary P.
使用高分辨率磁共振成像和基于体素的形态计量学方法，比较了14名首发抑郁症(MDD)的未服药女性参与者和13名健康对照女性(HC)的局部灰质体积。MDD组双侧扣带回腹侧前叶(VACC)和右侧杏仁核体积明显小于HC组。这些结果表明，女性MDD患者的VACC和杏仁核体积在发病时就出现了减少。(C)2007爱思唯尔爱尔兰有限公司。保留所有权利。
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional gray matter volumes between 14 medication-naive female participants with a first episode of major depressive disorder (MDD) and 13 female healthy comparison participants (HC). Volumes of bilateral ventral anterior cingulate cortex (vACC) and right amygdala were significantly smaller in the MDD group than in the HC group. These results suggest that volume reductions in vACC and amygdala in females with MDD are present at illness onset. (c) 2007 Elsevier Ireland Ltd. All rights reserved.