OCD with comorbid OCPD: A subtype of OCD?
OCD with comorbid OCPD: A subtype of OCD?
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DOI：
10.1016/j.jpsychires.2006.12.009
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发表时间：
2008-03-01
影响因子：
4.8
通讯作者：
Eisen, Jane L.
中科院分区：
文献类型：
--
作者：
Coles, Meredith E.;Pinto, Anthony;Eisen, Jane L.
目的：本研究探讨了使用共病强迫性人格障碍（OCPD）来识别强迫症（OCD）个体亚型的有效性。方法：本研究的数据来自一项正在进行的、纵向的OCD病程研究，包括对238名患有原发性和当前DSM-IV强迫症寻求治疗的受试者的摄入评估。结果：超过四分之一的受试者（N = 65，27%）符合合并OCPD的标准。与OCD-OCPD受试者相比，OCD + OCPD受试者首次出现OC症状时的年龄明显更小（p = 0.013），对称和囤积强迫，以及清洁，订购，重复和囤积强迫的比例更高（所有p < 0.01）。OCD + OCPD患者的共病焦虑障碍（p = 0.007）和回避型人格障碍（p = 0.006）发生率较高。OCD + OCPD受试者的整体功能评分也明显较低（p = 0.001）和更多的社会功能受损（p = 0.004），尽管在强迫症症状的总体严重程度上缺乏显著差异。我们的研究结果表明，患有强迫症和强迫性持续性人格障碍的个体在最初的强迫症症状发作时的年龄方面具有不同的临床特征，他们所经历的强迫症和强迫症的类型，以及精神科合并症。我们的研究结果，再加上家庭研究的数据显示，在一级亲属的强迫症先证者的OCPD的频率高于预期，表明与OCPD相关的强迫症可能代表一个特定的亚型的强迫症。需要进一步的研究来进一步确定这种亚型的有效性。(C)2007爱思唯尔有限公司版权所有。
Objective: The current study examined the validity of using comorbid obsessive-compulsive personality disorder (OCPD) to identify a subtype of individuals with obsessive-compulsive disorder (OCD).Method: Data for the current study were drawn from an ongoing, longitudinal study of the course of OCD and include intake assessments for 238 subjects with primary and current DSM-IV OCD who were treatment seeking.Results: More than one fourth of the subjects (N = 65, 27%) met criteria for comorbid OCPD. As compared to OCD-OCPD subjects, the OCD + OCPD subjects had a significantly younger age at onset of first OC symptoms (p = 0.013), and a higher rate of symmetry and hoarding obsessions, and cleaning, ordering, repeating, and hoarding compulsions (all p's < 0.01). Individuals with OCD + OCPD had higher rates of comorbid anxiety disorders (p = 0.007) and avoidant personality disorder (p = 0.006). The OCD + OCPD subjects also had significantly lower ratings of global functioning (p = 0.001) and more impaired social functioning (p = 0.004), despite a lack of significant differences on overall severity of OCD symptoms.Conclusions: Our findings indicate that individuals with both OCD and OCPD have distinct clinical characteristics in terms of age at onset of initial OC symptoms, the types of obsessions and compulsions they experience, and psychiatric comorbidity. Our findings, coupled with data from family studies showing a higher than expected frequency of OCPD in first degree relatives of OCD probands, suggest that OCD associated with OCPD may represent a specific subtype of OCD. Additional research is warranted to further establish the validity of this subtype. (C) 2007 Elsevier Ltd. All rights reserved.