Cholinergic neuron-like D-U87 cells promote polarization of allergic rhinitis T-helper 2 cells
Cholinergic neuron-like D-U87 cells promote polarization of allergic rhinitis T-helper 2 cells
复制标题
胆碱能神经元样 D-U87 细胞促进过敏性鼻炎 T-辅助 2 细胞的极化
DOI:
10.1002/alr.22467
复制
发表时间:
2019-10-28
影响因子:
6.4
通讯作者:
Tan, Guolin
中科院分区:
文献类型:
--
作者:
Liu, Honghui;Wang, Tiansheng;Tan, Guolin
Parasympathetic nerve hypersensitivity contributes to the severity of allergic rhinitis (AR), but the precise mechanism underlying neuroimmune regulation in patients with AR remains unclear. This study investigated the effect of cholinergic nerve inhibition on AR CD4+ T‐helper (Th)2‐cell polarization and the underlying regulatory mechanism in vitro.