Calcific panniculitis and nasopharyngeal cancer-associated adult-onset dermatomyositis: a case report and literature review

Calcific panniculitis and nasopharyngeal cancer-associated adult-onset dermatomyositis: a case report and literature review
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钙化性脂膜炎与鼻咽癌相关的成人起病性皮肌炎一例报告及文献复习

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发表时间:
2015
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通讯作者:
Araya Manapajon
Araya Manapajon
中科院分区:
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作者:
Manasmon Chairatchaneeboon;K. Kulthanan;Araya Manapajon

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脂膜炎是皮肌炎中一种罕见的皮肤表现。它不仅发生在特发性皮肌炎中,而且也很少发生在恶性肿瘤相关的皮肌炎中。成人发病的皮肌炎也不太可能出现皮肤钙质沉着。在恶性肿瘤相关的皮肌炎中,脂膜炎可能先于、同时或随后发生恶性肿瘤的诊断。我们报告了一名 26 岁泰国女性患有钙化性脂膜炎的病例,该女性患有与鼻咽癌相关的成人发病的皮肌炎。本例中钙化性脂膜炎的临床病程与恶性肿瘤的病程并不平行。尽管癌症已缓解,但钙化性脂膜炎仍可能在多年后出现。还提供了对先前报道的文献的彻底回顾。
Panniculitis is an uncommon cutaneous manifestation in dermatomyositis. It not only occurs in idiopathic dermatomyositis, but also rarely occurs in the setting of malignancy-associated dermatomyositis. Calcinosis cutis is also less likely to be found in adult-onset dermatomyositis. In malignancy-associated dermatomyositis, panniculitis can precede, concur, or follow the diagnosis of malignancy. We report the case of a 26-year-old Thai female with calcific panniculitis in the setting of adult-onset dermatomyositis associated with nasopharyngeal cancer. The clinical course of calcific panniculitis in our case was not parallel to the course of malignancy. Calcific panniculitis can appear many years after, despite the remission of the cancer. A thorough review of the previously reported literature is also provided.