Palladium(II)-Catalyzed Efficient C-3 Functionalization of Indoles with Benzylic and Allylic Alcohols under Co-Catalyst, Acid, Base, Additive and External Ligand-Free Conditions
Palladium(II)-Catalyzed Efficient C-3 Functionalization of Indoles with Benzylic and Allylic Alcohols under Co-Catalyst, Acid, Base, Additive and External Ligand-Free Conditions
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DOI：
10.1002/adsc.201300048
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发表时间：
2013-05-01
影响因子：
5.4
通讯作者：
Roy, Sujit
中科院分区：
文献类型：
--
作者：
Das, Debjit;Roy, Sujit
双（乙腈）氯化钯（II）配合物，PdCl2（MeCN）2，有效地催化吲哚与各种苄醇和烯丙醇在水分和空气不敏感条件下的区域选择性烷基化。值得注意的是，该反应不需要任何其他助催化剂、酸、碱、添加剂或外部配体。
The bis(acetonitrile)palladium(II) chloride complex, PdCl2(MeCN)2, efficiently catalyzes the regioselective alkylation of indoles with various benzylic and allylic alcohols under moisture and air insensitive conditions. Notably the reaction does not require any other co-catalyst, acid, base, additive, or external ligand.