Overcoming barriers to long-term graft survival.

Overcoming barriers to long-term graft survival.
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克服移植物长期存活的障碍。

DOI:
10.1053/j.ajkd.2005.12.044
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发表时间:
2006
期刊:
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子:
--
通讯作者:
B. Kaplan
B. Kaplan
中科院分区:
--
文献类型:
--
作者:
B. Kaplan

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尽管近年来肾移植物的短期生存率有所提高,但重点已转移到提高移植物长期生存率的挑战上。急性排斥反应、慢性移植肾肾病和心血管疾病与移植物失功和患者死亡相关。减少这种移植后并发症的可能性可能会提高移植物的长期存活率。此外,更好地了解各种免疫抑制疗法在降低移植物损伤风险方面的作用,将有助于临床医生为个体肾移植受者做出更明智的适当治疗方案决定。
Although short-term kidney graft survival has improved in recent years, the focus has shifted to the challenge of improving long-term graft survival. Acute rejection, chronic allograft nephropathy, and cardiovascular disease are associated with graft loss and patient death. Reducing the potential for such posttransplantation complications may improve long-term graft survival. In addition, gaining a better understanding of the role that various immunosuppressive therapies have in decreasing the risk for graft injury will help clinicians make better-informed decisions about appropriate treatment regimens for individual kidney transplant recipients.
血压升高预示同种异体肾移植受者发生急性排斥反应的风险。
DOI: 10.1046/j.1523-1755.2001.0590031158.x
发表时间: 2001
期刊: Kidney international.
影响因子: --
作者:
Cosio,FG;Pelletier,RP;Pesavento,TE;Henry,ML;Ferguson,RM;Mitchell,L;Lemeshow,S
通讯作者: Lemeshow,S
急性排斥反应的特征会增加慢性排斥反应的风险。
DOI: 10.1097/00007890-199910270-00023
发表时间: 1999
期刊: Transplantation
影响因子: 6.2
作者:
Humar,A;Kerr,S;Gillingham,KJ;Matas,AJ
通讯作者: Matas,AJ