Uncoupling growth from the cell cycle.
Uncoupling growth from the cell cycle.
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DOI：
10.1002/(sici)1521-1878(199804)20:4
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发表时间：
1998-04
期刊：
影响因子：
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通讯作者：
L. Johnston
中科院分区：
文献类型：
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作者：
L. Johnston
果蝇的翅膀是如何长到合适的大小和形状的？虽然细胞分裂与细胞命运模式的合作似乎是显而易见的，但几乎没有人知道这两个过程在发育过程中是如何协调的。最近的一篇论文发现，阻断细胞分裂将细胞生长与细胞分裂周期分离，显示出翅膀原基以比正常细胞更少的细胞达到正确比例的能力具有显着的灵活性。
How does a Drosophila wing grow to the appropriate size and shape? Although a collaboration of cell division with the patterning of cell fates seems obvious, almost nothing is known about how these two processes are coordinated during development. A recent paper finds that blocking cell division uncouples cell growth from the cell division cycle, displaying remarkable flexibility in the ability of the wing primordia to achieve the right proportions with fewer than normal cells.