Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae.
Distinct subpopulations of mechanosensory chordotonal organ neurons elicit grooming of the fruit fly antennae.
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DOI：
10.7554/elife.59976
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发表时间：
2020-10-26
期刊：
影响因子：
7.7
通讯作者：
Seeds AM
中科院分区：
文献类型：
--
作者：
Hampel S;Eichler K;Yamada D;Bock DD;Kamikouchi A;Seeds AM
不同的机械感觉神经元检测可以影响动物行为的不同机械力。然而，我们对这些神经元的解剖和生理多样性以及它们影响的行为的理解是有限的。我们先前发现黑腹果蝇触角的梳理是由触角机械感觉弦音器官，即约翰斯顿器官（JO）引起的（Hampel et al.，2015）。在这里，我们描述了解剖学和生理学上不同的JO机械感觉神经元亚群，每个引起触角梳理。我们表明，亚群项目在大脑中的不同，离散区和不同的机械刺激的触角在他们的反应。虽然每个亚群的激活eliferous触角梳理，不同的亚群也引起额外的行为，翅膀拍打或向后运动。我们的研究结果提供了一个全面的描述的多样性的机械感觉神经元的JO，并揭示了不同的JO亚群可以引起共同的和不同的行为反应。
Diverse mechanosensory neurons detect different mechanical forces that can impact animal behavior. Yet our understanding of the anatomical and physiological diversity of these neurons and the behaviors that they influence is limited. We previously discovered that grooming of the Drosophila melanogaster antennae is elicited by an antennal mechanosensory chordotonal organ, the Johnston’s organ (JO) (Hampel et al., 2015). Here, we describe anatomically and physiologically distinct JO mechanosensory neuron subpopulations that each elicit antennal grooming. We show that the subpopulations project to different, discrete zones in the brain and differ in their responses to mechanical stimulation of the antennae. Although activation of each subpopulation elicits antennal grooming, distinct subpopulations also elicit the additional behaviors of wing flapping or backward locomotion. Our results provide a comprehensive description of the diversity of mechanosensory neurons in the JO, and reveal that distinct JO subpopulations can elicit both common and distinct behavioral responses.