Stimulation strategies for electrical and magnetic modulation of cells and tissues.
Stimulation strategies for electrical and magnetic modulation of cells and tissues.
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DOI：
10.1186/s13619-023-00165-8
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发表时间：
2023-07-01
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电现象在许多生物过程中起着重要作用，包括细胞信号传导、早期胚胎发生、组织修复和重塑以及生物体的生长。电和磁效应已经在各种刺激策略和细胞类型上进行了研究，涉及细胞功能和疾病治疗。在这篇综述中，我们讨论了最近的进展，使用三种不同的刺激策略，即通过导电和压电材料的电刺激以及通过磁性材料的磁刺激，以调节细胞和组织的属性。这三种策略提供了不同的刺激途径，给定特定的材料特性。这篇综述将评估这些刺激策略在神经和肌肉骨骼研究中的潜在应用的材料特性和生物反应。
Electrical phenomena play an important role in numerous biological processes including cellular signaling, early embryogenesis, tissue repair and remodeling, and growth of organisms. Electrical and magnetic effects have been studied on a variety of stimulation strategies and cell types regarding cellular functions and disease treatments. In this review, we discuss recent advances in using three different stimulation strategies, namely electrical stimulation via conductive and piezoelectric materials as well as magnetic stimulation via magnetic materials, to modulate cell and tissue properties. These three strategies offer distinct stimulation routes given specific material characteristics. This review will evaluate material properties and biological response for these stimulation strategies with respect to their potential applications in neural and musculoskeletal research.