1,1'-Binaphthyl-2,2'-diyl phosphoroselenoyl chloride as a chiral molecular tool for the preparation of enantiomerically pure alcohols and amines.
1,1'-Binaphthyl-2,2'-diyl phosphoroselenoyl chloride as a chiral molecular tool for the preparation of enantiomerically pure alcohols and amines.
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1,1-联萘-2,2-二基磷硒酰氯作为手性分子工具，用于制备对映体纯的醇和胺。
DOI：
10.1021/ja060308b
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发表时间：
2006
影响因子：
15
通讯作者：
Kenji Morishita
中科院分区：
文献类型：
--
作者：
T. Murai;Daichi Matsuoka;Kenji Morishita
合成了对映体纯的含联萘基的硒代磷酰氯。这种磷硒酰氯被用来区分和解决简单的仲醇。还实现了通过氯化物与简单仲醇反应获得的非对映体纯的磷硒酸酯向对映体纯的醇和胺的立体特异性转化。
Enantiomerically pure phosphoroselenoyl chloride bearing a binaphthyl group was synthesized. This phosphoroselenoyl chloride was used to discriminate and resolve simple secondary alcohols. Stereospecific conversions of diastereomerically pure phosphoroselenoic acid esters, obtained by reaction of the chloride with simple secondary alcohols, to enantiomerically pure alcohols and amines were also achieved.