Impact of obsessive-compulsive symptoms in Tourette's syndrome on neuropsychological performancepcn
Impact of obsessive-compulsive symptoms in Tourette's syndrome on neuropsychological performancepcn
复制标题
抽动秽语综合症强迫症状对神经心理表现的影响pcn
DOI：
10.1111/j.1440-1819.2012.02319.x
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发表时间：
2012
影响因子：
11.9
通讯作者：
他
中科院分区：
文献类型：
--
作者：
Natsumi Matsuda;Toshiaki Kono;Maiko Nonaka;他
目的：虽然抽动秽语综合征（TS）神经心理损伤的不一致已经与强迫症等共病疾病进行了讨论，但很少有研究关注与 TS 相关的强迫症状（OCS）的具体维度，例如攻击性和对称性。本研究的目的是探讨特定 TS 相关 OCS 对神经心理学表现的影响。方法：在 33 名 TS 参与者和 18 名健康对照组中进行了一系列检查注意力和执行功能的神经心理学任务。将具有攻击性 OCS 的 TS (n= 11) 的神经心理学表现与不具有攻击性 OCS 的 TS (n= 22) 以及使用曼科瓦控制年龄的对照进行比较。与攻击性相同，我们通过对称性比较了三组的表现：使用对称性 OCS 的 TS (n= 14)、不使用对称性 OCS 的 TS (n= 19) 和对照组。 结果：使用攻击性 OCS 的 TS 参与者比没有使用攻击性 OCS 的参与者更容易犯持续性错误。整体 OCS 严重程度和抽动严重程度与任何神经心理学表现均不相关。在使用和不使用对称性 OCS 的 TS 参与者之间没有检测到显着差异。结论：TS 中的神经心理缺陷可能不受整体 OCS 严重程度的影响，而是受特定 TS 相关 OCS 的影响。
Aim:Although inconsistencies in neuropsychological impairments in Tourette's syndrome (TS) have been discussed with respect to comorbid disorders, such as obsessive–compulsive disorder, few studies have focused on the specific dimensions of obsessive–compulsive symptoms (OCS) related to TS, such as aggression and symmetry. The aim of this study was to explore the impact of specific TS‐related OCS on neuropsychological performance.Methods:A series of neuropsychological tasks examining attention and executive functioning were performed in groups of 33 TS participants and 18 healthy controls. The neuropsychological performance of TS with Aggression OCS (n= 11) were compared to TS without Aggression OCS (n= 22) and controls by usingmancovacontrolling for age. In the same way as Aggression, we compared the performance of three groups by Symmetry: TS with Symmetry OCS (n= 14), TS without Symmetry OCS (n= 19) and controls.Results:TS participants with Aggression OCS tended to make more perseverative errors than those without. Global OCS severity and tic severity did not correlate with any neuropsychological performances. No significant differences were detected between TS participants with and without Symmetry OCS.Conclusion:Neuropsychological deficits in TS might be affected not by global OCS severity but by specific TS‐related OCS.