First report of Nitzschia navis-varingica in the Mediterranean Sea and growth stimulatory effects of Nitzschia navis-varingica, Chrysochromulina alifera and Heterocapsa pygmaea on different mammalian cell types
First report of Nitzschia navis-varingica in the Mediterranean Sea and growth stimulatory effects of Nitzschia navis-varingica, Chrysochromulina alifera and Heterocapsa pygmaea on different mammalian cell types
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DOI：
10.1007/s11033-018-4195-7
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发表时间：
2018-08-01
影响因子：
2.8
通讯作者：
Sahin, Merve
中科院分区：
文献类型：
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作者：
Ayaz, Furkan;Eker-Develi, Elif;Sahin, Merve
一种底栖硅藻，Nitzschia navis-varingica首次在地中海被发现。研究了这种硅藻与附着菌Chrysochromulina alifera和从地中海东北海岸分离的甲藻Heterocapsa pygmaea对前列腺、乳腺癌和成纤维细胞系的影响。藻类提取物对这些细胞系没有任何毒性作用，并且对细胞具有生长刺激作用，而不区分细胞类型。我们的研究结果表明，这些藻类提取物在人类和动物的饮食中的组织修复和细胞生长促进添加剂中具有潜在的用途。此外，这些藻类提取物具有用作化妆品工业中的皮肤活化霜的天然资源和用作特应性药物中的伤口愈合剂的潜力。
A benthic diatom, Nitzschia navis-varingica was found for the first time in the Mediterranean Sea. Effects of this diatom species together with the haptophyte Chrysochromulina alifera and the dinoflagellate Heterocapsa pygmaea isolated from the northeastern Mediterranean Sea coast on prostate, breast cancer and fibroblast cell lines were investigated. Algal extracts did not exert any toxic effect on these cell lines and it had growth stimulatory impact on the cells without discrimination of cell type. Our results suggest potential use of these algal extracts in tissue repair and cell growth boosting additive in the diet of humans as well as animals. Moreover, these algal extracts have potential to be used as natural resource in the skin vitalizing creams of cosmetics industry and as wound healing agents in the atopic drugs.