Solitary pulmonary MALT lymphoma presenting crystal-storing histiocytosis
Solitary pulmonary MALT lymphoma presenting crystal-storing histiocytosis
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孤立性肺 MALT 淋巴瘤表现为晶体储存组织细胞增多症
DOI：
10.11406/rinketsu.57.1032
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
川上恵基
中科院分区：
文献类型：
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作者：
永春圭規;景山裕紀;渡邊拓弥;山口貴則;伊藤竜吾;馬場洋一郎;桝屋正浩;大橋璃子;川上恵基
晶体储存组织细胞增生症（CSH）的特征是大量组织细胞聚集，胞浆内有结晶的免疫球蛋白，通常与血液恶性肿瘤有关。一名69岁的男性，6年前曾因肾盂癌接受左肾切除术和化疗，此后每年接受CT扫描，在目前的表现前2年，在他的肺左下叶发现一个小结节。由于肺结节的进展，他因怀疑肺癌而接受了肺叶切除术。他最终被诊断为CSH伴粘膜相关淋巴组织淋巴瘤IAE期。在没有进一步治疗的情况下，他在术后10个月内没有复发。因为据报道CSH可能是血液系统恶性肿瘤的初始表现，所以仔细观察和评估这些血液疾病的存在是必不可少的。
Crystal-storing histiocytosis (CSH) is characterized by the accumulation of large histiocytes with intracytoplasmic crystallized immunoglobulin and is typically associated with hematological malignancies. A 69-year-old man, who had a history of left nephrectomy and chemotherapy for renal pelvic cancer six years earlier, had received a CT scan every year thereafter and a small nodule was found in the left lower lobe of his lungs two years prior to the current presentation. Because of progression of this pulmonary nodule, he underwent pulmonary lobectomy on suspicion of lung cancer. He was ultimately diagnosed as having CSH accompanied by mucosa-associated lymphoid tissue lymphoma stage IAE. In the absence of further treatment, he has been well with no recurrence of the disease for 10 months postoperatively. Because CSH could reportedly be an initial presentation of hematological malignancies, careful observation and evaluation for the presence of these blood disorders is essential.