Linkage disequilibrium and recombination in hominid mitochondrial DNA
Linkage disequilibrium and recombination in hominid mitochondrial DNA
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DOI：
10.1126/science.286.5449.2524
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发表时间：
1999-12-24
期刊：
影响因子：
56.9
通讯作者：
Smith, JM
中科院分区：
文献类型：
--
作者：
Awadalla, P;Eyre-Walker, A;Smith, JM
人类线粒体DNA仅从父母一方遗传且因此不发生重组这一假设是有问题的。人类和黑猩猩线粒体DNA的连锁不平衡随着位点之间距离的增加而降低，这种模式只能归因于一种机制：重组。
The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable, Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites, This pattern can be attributed to one mechanism only: recombination.