COPPER, IRON, AND ZINC CONTENTS OF HUMAN-MILK AT EARLY STAGES OF LACTATION
COPPER, IRON, AND ZINC CONTENTS OF HUMAN-MILK AT EARLY STAGES OF LACTATION
复制标题
DOI：
10.1093/ajcn/37.3.443
复制
发表时间：
1983-01-01
影响因子：
7.1
通讯作者：
BARNHART, H
中科院分区：
文献类型：
--
作者：
FEELEY, RM;EITENMILLER, RR;BARNHART, H
研究了102名美国母亲的早期母乳中Cu、Fe和Zn的含量与哺乳期、产前矿物质补充剂的摄入量、母亲年龄、胎次和哺乳期史的关系。在哺乳期早期（产后4 ~ 7 d）采集412只样本；过渡期（产后10-14天）；和成熟（产后30-45天）。在过渡期和成熟期，分别采集傍晚（PM）和清晨（AM）采食的代表性样品。只观察到铁的浓度日变化。各元素浓度在泌乳期各阶段均显著下降，其中锌下降幅度最大。Cu， Fe和Zn含量（平均值为+-）。SEM[平均标准误差])为104.1 .+-。5.4, 96.5 .+-。6.5和520 .+-。20 .mu。G /100 G在早期过渡乳中；93.9。+ -。3.6, 85.4 .+-。4.5和410 .+-。10 .mu。过渡性牛奶中每100克含有84.7 .+-。3.8, 76.1 .+-。3.8和290 .+-。10 .mu。G /100 G成熟乳。牛奶中铜和锌的含量与母亲是否服用含有这些元素的膳食补充剂之间没有明显的关系。未发现母亲年龄、胎次或哺乳期史与母乳元素含量有显著相关性。据估计，完全母乳喂养的婴儿将获得大约100万美元。在新生儿期分别添加0.11、0.10和0.50 mg/kg /天的Cu、Fe和Zn。
The Cu, Fe and Zn contents of early milk from 102 American mothers were examined in relation to stage of lactation, intake of prenatal mineral supplements, maternal age, parity and previous history of lactation. A total of 412 samples was collected at 3 stages of lactation: early transitional (4-7 days postpartum); transitional (10-14 days postpartum); and mature (30-45 days postpartum). For the transitional and mature stages, representative samples of late evening (PM) and early morning (AM) feedings were collected. Diurnal variation in concentration was observed only for Fe. Concentrations of all elements decreased significantly at successive stages of lactation with Zn showing the greatest decline. Cu, Fe and Zn contents (means .+-. SEM [standard error of the mean]) were 104.1 .+-. 5.4, 96.5 .+-. 6.5 and 520 .+-. 20 .mu.g/100 g in early transitional milk; 93.9 .+-. 3.6, 85.4 .+-. 4.5 and 410 .+-. 10 .mu.g/100 g in transitional milk and 84.7 .+-. 3.8, 76.1 .+-. 3.8 and 290 .+-. 10 .mu.g/100 g in mature milk, respectively. No significant relationship was found between levels of Cu and Zn in milk and whether mothers had taken dietary supplements containing these elements. No significant correlations were found between maternal age, parity or previous history of lactation and the elemental content of milk. It was estimated that fully breast-fed infants would receive .apprx. 0.11, 0.10 and 0.50 mg/kg per day of Cu, Fe and Zn, respectively, during the neonatal period.