Do Topical Repellents Divert Mosquitoes within a Community? - Health Equity Implications of Topical Repellents as a Mosquito Bite Prevention Tool
Do Topical Repellents Divert Mosquitoes within a Community? - Health Equity Implications of Topical Repellents as a Mosquito Bite Prevention Tool
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DOI：
10.1371/journal.pone.0084875
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发表时间：
2013-12-20
期刊：
影响因子：
3.7
通讯作者：
Moore, Sarah Jane
中科院分区：
文献类型：
--
作者：
Maia, Marta Ferreira;Onyango, Sangoro Peter;Moore, Sarah Jane
目的：驱避剂不能杀死蚊子，只是减少人与病媒的接触。因此，不使用驱避剂但居住在驱避剂使用者附近的个人可能比其他人经历更多的叮咬。本研究的目的是衡量是否发生转移，从家庭使用驱虫剂，那些不使用repellents.Methods：这项研究是在坦桑尼亚的三个村庄使用15%避蚊胺和安慰剂洗剂。所有家庭都得到了长效驱虫蚊帐。调查了三种覆盖情况：完全覆盖（所有家庭都给予15%的避蚊胺），不完全覆盖（80%的家庭给予15%的避蚊胺和20%的安慰剂）和没有覆盖（所有家庭都给予安慰剂）。采用交叉研究设计，在10周内每周轮换覆盖场景。安慰剂洗剂被随机分配给不完全覆盖场景中的家庭。据报告，遵守率接近100%。通过吸入静止的蚊子来测量蚊子密度。数据进行了分析，使用负二项回归models.Findings：驱蚊剂用户一直在他们的住所蚊子少。在每个人都被给予15%避蚊胺的村庄，蚊子的静止密度不到没有覆盖的家庭的一半（发病率比[IRR]=0.39（95%置信区间[CI]：0.25-0.60）; p
Objectives: Repellents do not kill mosquitoes - they simply reduce human-vector contact. Thus it is possible that individuals who do not use repellents but dwell close to repellent users experience more bites than otherwise. The objective of this study was to measure if diversion occurs from households that use repellents to those that do not use repellents.Methods: The study was performed in three Tanzanian villages using 15%-DEET and placebo lotions. All households were given LLINs. Three coverage scenarios were investigated: complete coverage (all households were given 15%-DEET), incomplete coverage (80% of households were given 15%-DEET and 20% placebo) and no coverage (all households were given placebo). A crossover study design was used and coverage scenarios were rotated weekly over a period of ten weeks. The placebo lotion was randomly allocated to households in the incomplete coverage scenario. The level of compliance was reported to be close to 100%. Mosquito densities were measured through aspiration of resting mosquitoes. Data were analysed using negative binomial regression models.Findings: Repellent-users had consistently fewer mosquitoes in their dwellings. In villages where everybody had been given 15%-DEET, resting mosquito densities were fewer than half that of households in the no coverage scenario (Incidence Rate Ratio [IRR]=0.39 (95% confidence interval [CI]: 0.25-0.60); p