Comparative Effectiveness of Glucose and Sucrose in Enhancement of Hypersalimentation and Salt Hypertension.∗
Comparative Effectiveness of Glucose and Sucrose in Enhancement of Hypersalimentation and Salt Hypertension.∗
复制标题
葡萄糖和蔗糖在增强高盐血症和盐高血压方面的比较效果。*
DOI：
10.3181/00379727-123-31491
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发表时间：
1966
影响因子：
--
通讯作者：
O. Hall
中科院分区：
文献类型：
--
作者：
C. Hall;O. Hall
总结在饮用溶液中加入5%浓度的葡萄糖或蔗糖，可显著增加大鼠消耗1%盐水的量和盐性高血压的发生。心脏肥大和病变同等增加。一个奇怪的，至今无法解释的发现是，尽管肾脏肿大伴随着生理盐水或蔗糖盐水溶液的消耗，但葡萄糖盐水的情况并非如此。在这里，肾脏重量没有超过对照组，肾血管病变虽然存在，但不像喝其他盐溶液时那么明显。
Summary The quantity of 1% saline consumed and the development of salt hypertension in rats were comparably enhanced by addition of either glucose or sucrose in 5% concentration to the drinking solution. Cardiac hypertrophy and lesions were equivalently increased. A curious, and as yet unexplained finding, is that whereas kidney enlargement accompanied consumption of either saline or sucrose-saline solution, such was not the case with glucose-saline. Here the kidney weight did not exceed that of controls, and reno-vascular lesions although present were less pronounced than when other saline solutions were drunk.