Generalized log-rank test for mixed interval-censored failure time data
Generalized log-rank test for mixed interval-censored failure time data
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DOI：
10.1002/sim.1746
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发表时间：
2004-05-30
影响因子：
2
通讯作者：
Sun, JG
中科院分区：
文献类型：
--
作者：
Zhao, Q;Sun, JG
本文考虑了在临床试验和流行病学研究中经常出现的混合区间删失失效时间数据下的非参数处理比较问题。所谓混合区间删失数据，是指所关注的生存时间被观察到属于一个区间或被右删失。对于这个问题，我们推广了最常用的对数秩检验的右删失生存数据。数值研究进行了评估和比较所提出的测试与现有的方法，这表明所提出的方法工作得很好。我们应用该方法的数据集所产生的艾滋病队列研究，动机的研究。版权所有（C）2004约翰威利父子有限公司。
This paper considers the problem of non-parametric treatment comparisons when mixed interval-censored failure time data are available, which often occurs in clinical trials and epidemiological studies. By mixed interval-censored data, we mean that the survival time of interest is observed to belong to an interval or to be right-censored. For the problem, we generalize the most commonly used log-rank test for right-censored survival data. Numerical studies are conducted and reported to evaluate and compare the proposed test with the existing method, which indicate that the presented method works well. We apply the method to a data set arising from an AIDS cohort study, that motivated the study. Copyright (C) 2004 John Wiley Sons, Ltd.