Erythema and pigmentation
Erythema and pigmentation
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DOI：
10.1034/j.1600-0781.2002.180204.x
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发表时间：
2002-04-01
影响因子：
2.6
通讯作者：
Hönigsmann, H
中科院分区：
文献类型：
--
作者：
Hönigsmann, H
暴露在阳光或人工紫外线辐射下的急性临床效应包括红斑（晒伤）和色素沉着（晒黑）以及表皮增厚，特别是角质层（“Lichtschwiele”）。还有其他生物反应，如免疫抑制和维生素D的光合作用，这里不讨论。大多数人类暴露在阳光下的紫外线辐射，但其他来源，如光疗灯、日光浴床、弧焊设备和无屏蔽的荧光灯和钨卤灯也会造成类似的影响。人类皮肤的个体红斑和晒黑反应基本上是由基因决定的。研究表明MSH受体的多态性可能起作用(1)，尽管其他基因也可能参与其中。
The acute clinical effects of exposure to sunlight or artificial UV radiation consist of erythema (sunburn) and pigmentation (tanning) as well as thickening of the epidermis, in particular the stratum corneum (‘Lichtschwiele’). There are also other biological reactions, such as immunosuppression and the photosynthesis of vitamin D, which will not be discussed here. Most human UV radiation exposure is to sunlight, but other sources such as phototherapy lamps, sunbeds, arc-welding apparatus and unshielded fluorescent and tungsten-halogen lamps can cause similar effects. The individual erythema and tanning responses of human skin are basically genetically determined. Studies indicate a possible role for polymorphisms in the MSH receptor (1), although other genes may also be involved.