The John Charnley Award. Wear is a function of use, not time.
The John Charnley Award. Wear is a function of use, not time.
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DOI：
10.1097/00003086-200012000-00005
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发表时间：
2000-12-01
影响因子：
4.2
通讯作者：
Amstutz, H C
中科院分区：
文献类型：
--
作者：
Schmalzried, T P;Shepherd, E F;Amstutz, H C
使用经过验证的二维、基于边缘检测的计算机算法，根据数字图像评估 37 个髋关节置换术中的聚乙烯磨损（线性穿透）。使用计步器、步数活动监视器和简单的视觉模拟量表评估患者的活动。联合使用与磨损相关的置信度为 90%。如果没有三个公认的异常值，磨损与使用高度相关。视觉模拟量表活动评级与 24 个标准聚乙烯髋关节置换术的磨损显着相关。单变量回归分析表明，男性性别、身高、体重（均与男性性别高度相关）和髋关节旋转中心与磨损显着相关。多元回归分析表明，男性、股骨偏移量和 Hylamer 与磨损显着相关。根据 24 个标准聚乙烯髋关节置换术的磨损和活动数据，70 公斤患者体重每百万次循环的平均体积磨损率为 30 mm3。这种独特的体内结果可以被认为是髋关节模拟器研究中标准聚乙烯的目标磨损率。
Polyethylene wear (linear penetration) in 37 hip replacements was assessed from digital images using a validated two-dimensional, edge detection-based computer algorithm. Patient activity was assessed with a pedometer, a step activity monitor and a simple visual analog scale. Joint use was related to wear at the 90% confidence level. Without three recognized outliers, wear was highly correlated to use. The visual analog scale activity rating was significantly related to wear for the 24 hip replacements with standard polyethylene. Univariate regression analysis indicated that male gender, height, weight (which were both highly correlated to male gender) and hip center of rotation were significantly correlated to wear. Multivariate regression analysis indicated that male gender, femoral off-set, and Hylamer were significantly correlated to wear. Based on the wear and activity data from the 24 hip replacements with standard polyethylene, the average volumetric wear rate per million cycles with a 70 kg patient weight was 30 mm3. This unique in vivo result can be considered a target wear rate for standard polyethylene in hip simulator studies.