Processing of location and pattern changes of natural sounds in the human auditory cortex
Processing of location and pattern changes of natural sounds in the human auditory cortex
复制标题
DOI：
10.1016/j.neuroimage.2007.01.007
复制
发表时间：
2007-04-15
期刊：
影响因子：
5.7
通讯作者：
Kaiser, Jochen
中科院分区：
文献类型：
--
作者：
Altmann, Christian F.;Bledowski, Christoph;Kaiser, Jochen
对于听觉模式和空间信息的处理，已经提出了平行的皮层通路。我们用人类功能磁共振成像(FMRI)和单独的脑电(EEG)记录在同一受试者中测试了这种分离，这些受试者在事件相关范式中被动地听了四个重复的空间动物发声序列。序列之间的转换构成了听觉模式、位置或两者的模式+位置的改变。这一过程使我们能够研究与个体刺激差异无关的自然听觉“什么”和“哪里”变化的大脑皮层相关性。对于模式改变，我们观察到双侧颞上前回和颞上沟、极平面、外侧赫氏回和颞前平面的fMRI反应显著增加。对于位置改变，双侧后上回和颞平面的fMRI反应显著增加。这两种类型的改变重叠出现在外侧前平面和后颞叶上回。对源事件相关电位(ERPs)的分析显示，对位置的处理比对模式变化的处理更快。因此，我们的数据表明，听觉空间和模式变化的被动处理在人脑中在时间和解剖上都是分离的。在声音识别加工中，颞叶上叶更前部的主要作用支持了该区域作为听觉模式处理流的一部分的作用，而听觉刺激的空间加工似乎是由颞叶上叶更后部的部分调节的。(C)2007 Elsevier Inc.保留所有权利。
Parallel cortical pathways have been proposed for the processing of auditory pattern and spatial information, respectively. We tested this segregation with human functional magnetic resonance imaging (fMRI) and separate electroencephalographic (EEG) recordings in the same subjects who listened passively to four sequences of repetitive spatial animal vocalizations in an event-related paradigm. Transitions between sequences constituted either a change of auditory pattern, location, or both pattern + location. This procedure allowed us to investigate the cortical correlates of natural auditory "what" and "where" changes independent of differences in the individual stimuli. For pattern changes, we observed significantly increased fMRI responses along the bilateral anterior superior temporal gyrus and superior temporal sulcus, the planum polare, lateral Heschl's gyrus and anterior planum temporale. For location changes, significant increases of fMRI responses were observed in bilateral posterior superior temporal gyrus and planum temporale. An overlap of these two types of changes occurred in the lateral anterior planum temporale and posterior superior temporal gyrus. The analysis of source event-related potentials (ERPs) revealed faster processing of location than pattern changes. Thus, our data suggest that passive processing of auditory spatial and pattern changes is dissociated both temporally and anatomically in the human brain. The predominant role of more anterior aspects of the superior temporal lobe in sound identity processing supports the role of this area as part of the auditory pattern processing stream, while spatial processing of auditory stimuli appears to be mediated by the more posterior parts of the superior temporal lobe. (C) 2007 Elsevier Inc. All rights reserved.