Nonpalpable in situ ductal carcinoma of the breast. Predictors of multicentricity and microinvasion and implications for treatment.
Nonpalpable in situ ductal carcinoma of the breast. Predictors of multicentricity and microinvasion and implications for treatment.
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乳腺不可触及的原位导管癌。
DOI：
10.1001/archsurg.1989.01410010035007
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发表时间：
1989
影响因子：
--
通讯作者：
J. Singer
中科院分区：
文献类型：
--
作者：
G. Schwartz;A. Patchefsky;Sidney D. Finklestein;Sae H. Sohn;A. Prestipino;S. Feig;J. Singer
对50例未触及导管原位癌（DCIS）的乳腺进行了检查，以确定是否存在微浸润、多中心性和受累导管的数量，以确定活检标本是否可以预测其余乳腺的发现。当DCIS是偶然发现时，较少的导管受累，没有发现微浸润或多中心的证据;实性和筛状DCIS很少是多中心或微浸润的;微乳头状DCIS通常是多中心的，很少是微浸润的;粉刺癌更可能是微浸润和多中心的。导管原位癌作为一个偶然发现，可以通过切除单独治疗;乳头状和微乳头状DCIS最好的治疗针对整个乳房，虽然腋窝淋巴结清扫可能不需要。粉刺癌的治疗应包括整个乳房和腋窝淋巴结。
Fifty breasts with nonpalpable ductal carcinoma in situ (DCIS) were examined for the presence of microinvasion, multicentricity, and number of involved ducts to see if the biopsy specimen could have predicted the findings in the remainder of the breast. When DCIS was an incidental finding, fewer ducts were involved and no evidence of either microinvasion or multicentricity was found. Solid and cribriform DCIS were rarely multicentric or microinvasive; micropapillary DCIS was often multicentric, rarely microinvasive; comedocarcinoma was more likely to be both microinvasive and multicentric. Ductal carcinoma in situ as an incidental finding may be treated by excision alone; papillary and micropapillary DCIS are best treated by therapy aimed at the entire breast, although axillary dissection may not be required. Therapy for comedocarcinomas should include the entire breast and the axillary nodes.