ANALYSIS OF THE NUCLEOTIDE-SEQUENCE OF CHROMOSOME-VI FROM SACCHAROMYCES-CEREVISIAE
ANALYSIS OF THE NUCLEOTIDE-SEQUENCE OF CHROMOSOME-VI FROM SACCHAROMYCES-CEREVISIAE
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DOI：
10.1038/ng0795-261
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发表时间：
1995-07-01
期刊：
影响因子：
30.8
通讯作者：
EKI, T
中科院分区：
文献类型：
--
作者：
MURAKAMI, Y;NAITOU, M;EKI, T
酿酒酵母VI号染色体全长270kb，含有129个预测或已知基因(300bp或更长)。其中37个(28%)以前已经确定。在92个新基因中，有39个与之前发现的基因高度同源。将局部序列基序与ARS活性区域和具有完美ARS核心序列的非活性位点进行比较，以检验这些基序与ARS活性之间的关系。在活性ARS基因座的3‘侧翼序列中主要观察到附加的ARS序列。
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VI (270 kb) has revealed that it contains 129 predicted or known genes (300 bp or longer). Thirty-seven (28%) of which have been identified previously. Among the 92 novel genes, 39 are highly homologous to previously identified genes. Local sequence motifs were compared to active ARS regions and inactive loci with perfect ARS core sequences to examine the relationship between these motifs and ARS activity. Additional ARS sequences were predominantly observed in 3' flanking sequences of active ARS loci.