Impact of fatigue in multiple sclerosis:: the Fatigue Impact Scale for Daily Use (D-FIS)
Impact of fatigue in multiple sclerosis:: the Fatigue Impact Scale for Daily Use (D-FIS)
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DOI：
10.1177/1352458506073528
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发表时间：
2007-06-01
影响因子：
5.8
通讯作者：
Ruiz-Martinez, I.
中科院分区：
文献类型：
--
作者：
Benito-Leon, J.;Martinez-Martin, P.;Ruiz-Martinez, I.
目的日常使用疲劳影响量表（D-FIS）是一个由8个项目组成的测量主观疲劳的工具。本研究旨在确定的度量属性的D-FIS在多发性硬化症（MS）patients.Methods 68例与操作定义的MS和疲劳（54.8%的样本）进行了D-FIS。同时应用MS的临床指标、Montgomery-Asberg抑郁量表（MADRS）和多发性硬化症功能评估（FAMS）。结果完全可计算数据率为95.6%，下限效应和上限效应均为1.54%，项目与总项目的相关系数为0.62（项目1）~ 0.84（项目6）;克朗巴赫α =0.91;项目同质性=0.55;测量标准误= 3.18;与其他疲劳测量的收敛效度= -0.57（VAS-F）; 0.52（GPF）;和0.46（MFI-一般疲劳）。重测信度（ICC）=0.81。D-FIS与健康相关生活质量（HRQoL）（FAMS）之间有较强的相关性（rs = 0.70）。结论D-FIS是一种测量MS相关性疲劳的有效工具，MS相关性疲劳是与患者HRQoL恶化相关的常见症状。
Objective The Fatigue Impact Scale for Daily Use (D-FIS) is an eight-item instrument designed to measure subjective daily experience of fatigue. This study sought to determine the metric properties of the D-FIS in multiple sclerosis (MS) patients.Methods Sixty-eight patients with operationally-defined MS and fatigue (54.8% of the sample) underwent the D-FIS. Usual clinical measures for MS, the Montgomery-Asberg Depression Rating Scale (MADRS) and the Functional Assessment of Multiple Sclerosis (FAMS) were also applied. In addition, patients with fatigue completed the Fatigue Descriptive Scale, the Multidimensional Fatigue Inventory (MFI), a Visual Analogue Scale for Fatigue (VAS-F), and a Global Perception of Fatigue Scale (GPF).Results Full computable data, 95.6%; both floor and ceiling effect= 1.54%; item-total correlation =0.62 (item 1) to 0.84 (item 6); Cronbach's alpha =0.91; item homogeneity =0.55; standard error of measurement= 3.18; convergent validity with other fatigue measures = -0.57 (VAS-F); 0.52 (GPF); and 0.46 (MFI-general fatigue). Test-retest reliability (ICC)=0.81. There was a strong association between health-related quality of life (HRQoL) (FAMS) and D-FIS (rs = 0.70).Conclusions In this study, D-FIS proved to be a feasible and valid instrument for measuring MSrelated fatigue, a frequent symptom associated with deterioration of patients' HRQoL.