Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320-MDCT: the CT angiography and perfusion methods of the CORE320 multicenter multinational diagnostic study.
Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320-MDCT: the CT angiography and perfusion methods of the CORE320 multicenter multinational diagnostic study.
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DOI：
10.2214/ajr.10.5689
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发表时间：
2011-10
期刊：
影响因子：
--
通讯作者：
Lima JA
中科院分区：
文献类型：
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作者：
George RT;Arbab-Zadeh A;Cerci RJ;Vavere AL;Kitagawa K;Dewey M;Rochitte CE;Arai AE;Paul N;Rybicki FJ;Lardo AC;Clouse ME;Lima JA
冠状动脉 MDCT 血管造影已被证明是诊断阻塞性冠状动脉疾病 (CAD) 的准确无创工具。与其他无创检测方法相比，其诊断狭窄百分比的灵敏度和阴性预测值是无与伦比的。然而，就目前的形式而言，它没有提供有关 CAD 生理影响的信息，并且不能很好地预测心肌缺血。 CORE320是一项多中心跨国诊断研究，主要目的是与传统冠状动脉造影和SPECT心肌灌注成像的参考标准相比，评估320-MDCT对疑似CAD患者冠状动脉管腔狭窄和相应心肌灌注不足的诊断准确性。我们的目的是描述CORE320研究的CT采集、重建和分析方法。
Coronary MDCT angiography has been shown to be an accurate noninvasive tool for the diagnosis of obstructive coronary artery disease (CAD). Its sensitivity and negative predictive value for diagnosing percentage of stenosis are unsurpassed compared with those of other noninvasive testing methods. However, in its current form, it provides no information regarding the physiologic impact of CAD and is a poor predictor of myocardial ischemia. CORE320 is a multicenter multinational diagnostic study with the primary objective to evaluate the diagnostic accuracy of 320-MDCT for detecting coronary artery luminal stenosis and corresponding myocardial perfusion deficits in patients with suspected CAD compared with the reference standard of conventional coronary angiography and SPECT myocardial perfusion imaging. We aim to describe the CT acquisition, reconstruction, and analysis methods of the CORE320 study.